0000000001085062

AUTHOR

Vital Vialas

showing 2 related works from this author

A multicentric study to evaluate the use of relative retention times in targeted proteomics.

2016

Despite the maturity reached by targeted proteomic strategies, reliable and standardized protocols are urgently needed to enhance reproducibility among different laboratories and analytical platforms, facilitating a more widespread use in biomedical research. To achieve this goal, the use of dimensionless relative retention times (iRT), defined on the basis of peptide standard retention times (RT), has lately emerged as a powerful tool. The robustness, reproducibility and utility of this strategy were examined for the first time in a multicentric setting, involving 28 laboratories that included 24 of the Spanish network of proteomics laboratories (ProteoRed-ISCIII). According to the results…

0301 basic medicineMultiple reaction monitoringProteomicsBiomedical ResearchComputer scienceBiophysicsLiquid chromatographyContext (language use)BioinformaticsBiochemistry03 medical and health sciencesInter-laboratory validationTargeted proteomicsObserver VariationReproducibilityResearchReproducibility of ResultsAnalytical scienceReference StandardsStandardizationReproducibilityCell and molecular biologyTargeted proteomics030104 developmental biologyBiological significanceBiochemical engineeringRetention timeChromatography LiquidJournal of proteomics
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Surfing transcriptomic landscapes. A step beyond the annotation of chromosome 16 proteome

2013

All participating laboratories are members of ProteoRed-ISCIII.-- et al.

ProteomicsProteomeSequence analysisBioinformaticsBiologyMicrobiologíaENCODEProteomicsBiochemistryMass SpectrometryTranscriptome03 medical and health sciencesAnnotationChromosome 16RNA-Seq. ENCODEHuman proteome projectHumansHuman proteome projectTranscriptomics030304 developmental biologyGenetics0303 health sciencesSequence Analysis RNA030302 biochemistry & molecular biologyGeneral ChemistryChromosome 163. Good healthProteomeTranscriptomeChromosomes Human Pair 16Chromatography Liquid
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