0000000001086759

AUTHOR

Delphine Weil

showing 3 related works from this author

Circulating levels of 3-hydroxymyristate, a direct quantification of endotoxaemia in noninfected cirrhotic patients

2019

IF 4.5; International audience; Background & AimsThe quantification of lipopolysaccharide (LPS) in biological fluids is challenging. We aimed to measure plasma LPS concentration using a new method of direct quantification of 3‐hydroxymyristate (3‐HM), a lipid component of LPS, and to evaluate correlations between 3‐HM and markers of liver function, endothelial activation, portal hypertension and enterocyte damage.MethodsPlasma from 90 noninfected cirrhotic patients (30 Child‐Pugh [CP]‐A, 30 CP‐B, 30 CP‐C) was prospectively collected. The concentration of 3‐HM was determined by high‐performance liquid chromatography coupled with mass spectrometry.Results3‐HM levels were higher in CP‐C patien…

LipopolysaccharidesLiver CirrhosisMalemedicine.medical_specialtyCirrhosisLipopolysaccharidePilot ProjectsSeverity of Illness IndexGastroenterologyEndothelial activationendotoxaemia03 medical and health scienceschemistry.chemical_compound0302 clinical medicineRisk Factors3-HydroxymyristateInternal medicineHumansMedicinebacterial translocationHepatic encephalopathyChromatography High Pressure LiquidAgedHepatologybusiness.industrycirrhosislipopolysaccharideportal hypertensionMiddle Agedmedicine.diseaseEndotoxemia3. Good healthLogistic ModelschemistryHepatic Encephalopathy030220 oncology & carcinogenesisMultivariate AnalysisPortal hypertension[SDV.IMM]Life Sciences [q-bio]/ImmunologyFemale030211 gastroenterology & hepatologyLiver function3-hydroxymyristatebusinessAcute Alcoholic HepatitisMyristic AcidsBiomarkersBlood Chemical Analysis
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A new method for the direct quantification of lipopolysaccharide by High Performance Liquid Chromatography coupled with Mass Spectrometry in non-infe…

2017

IF 13.246; International audience

[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology[ SDV.MHEP.HEG ] Life Sciences [q-bio]/Human health and pathology/Hépatology and GastroenterologyMarker of bacterial of translocation[SDV.MHEP.HEG] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology
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Is ribavirin actually useful for Genotype 1 cirrhotic patients who receive DAAs combination? An updated meta-analysis of randomized controlled trials

2015

[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology
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