0000000001088708

AUTHOR

Polati E

showing 2 related works from this author

Albumin replacement in patients with severe sepsis or septic shock.

2014

BACKGROUND: Although previous studies have suggested the potential advantages of albumin administration in patients with severe sepsis, its efficacy has not been fully established. METHODS: In this multicenter, open-label trial, we randomly assigned 1818 patients with severe sepsis, in 100 intensive care units (ICUs), to receive either 20% albumin and crystalloid solution or crystalloid solution alone. In the albumin group, the target serum albumin concentration was 30 g per liter or more until discharge from the ICU or 28 days after randomization. The primary outcome was death from any cause at 28 days. Secondary outcomes were death from any cause at 90 days, the number of patients with or…

Malemedicine.medical_specialtyALBUMIN SEPSIS SEVERE SEPSIS SEPTIC SHOCKSepsiSerum albuminSettore MED/41 - AnestesiologiaAged; Albumins; Female; Humans; Isotonic Solutions; Male; Middle Aged; Rehydration Solutions; Sepsis; Serum Albumin; Shock Septic; Survival Rate; Treatment OutcomeSepsisIntensive careAlbuminsSepsismedicineHumansalbumin replacementSurvival rateSerum AlbuminIsotonic SolutionAgedAged; Albumins; Female; Humans; Isotonic Solutions; Male; Middle Aged; Rehydration Solutions; Sepsis; Serum Albumin; Shock Septic; Survival Rate; Treatment Outcome; Medicine (all)SEPSISbiologybusiness.industrySeptic shockRehydration SolutionSepticMedicine (all)AlbuminSEPTIC SHOCKOrgan dysfunctionAlbuminShockGeneral MedicineMiddle Agedmedicine.diseaseShock SepticSurgerySurvival RateTreatment OutcomeAnesthesiaRelative riskRehydration Solutionsbiology.proteinFemalemedicine.symptomIsotonic SolutionsbusinessHuman
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Sufentanil sublingual tablet system. From rationale of use to clinical practice

2020

The control of post-operative pain in Italy and other western countries is still suboptimal. In recent years, the Sufentanil Sublingual Tablet System (SSTS; Zalviso; AcelRx Pharmaceuticals, Redwood City, CA, USA), which is designed for patient-controlled analgesia (PCA), has entered clinical practice. SSTS enables patients to manage moderate-to-severe acute pain during the first 72 postoperative hours directly in the hospital setting. However, the role of SSTS within the current framework of options for the management of post-operative pain needs to be better established. This paper presents the position on the use of SSTS of a multidisciplinary group of Italian Experts and provides protoco…

Pain PostoperativeAdministration SublingualAnalgesia Patient-ControlledClinical practiceNeuropathic painAcute PainSSTAnalgesics OpioidSSTSsufentanilclinical practice; neuropathic pain; SSTS; surgeryPractice Guidelines as TopicHumansPain ManagementSurgeryTablets
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