0000000001088979

AUTHOR

Martina Cirlini

0000-0001-6485-7589

showing 2 related works from this author

Gliadin-mediated production of polyamines by RAW264.7 macrophages modulates intestinal epithelial permeability in vitro

2015

AbstractCeliac disease (CD) is an immune-mediated enteropathy sustained by dietary gluten in susceptible individuals, and characterized by a complex interplay between adaptive and innate responses against gluten peptides (PTG). In a recent contribution we have demonstrated that the treatment with PTG induces the expression and activity of arginase in both murine macrophages and human monocytes from healthy subjects, thus suggesting a role for arginine and its metabolites in gluten-triggered response of these cells. Here we further explore this field, by addressing the effects of PTG on polyamine synthesis and release in murine RAW264.7 macrophages, and how they affect epithelial permeabilit…

Intestinal permeabilityArginineArginaseInflammationBiologyIntestinal permeabilitymedicine.diseaseIn vitroGliadinCell biologyArginasechemistry.chemical_compoundBiochemistrychemistrymedicinePutrescinebiology.proteinPolyaminesMolecular MedicineCeliac diseaseSecretionmedicine.symptomGliadinMolecular BiologyBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
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Open Field Study of Some Zea mays Hybrids, Lipid Compounds and Fumonisins Accumulation

2015

Lipid molecules are increasingly recognized as signals exchanged by organisms interacting in pathogenic and/or symbiotic ways. Some classes of lipids actively determine the fate of the interactions. Host cuticle/cell wall/membrane components such as sphingolipids and oxylipins may contribute to determining the fate of host–pathogen interactions. In the present field study, we considered the relationship between specific sphingolipids and oxylipins of different hybrids of Zea mays and fumonisin by F. verticillioides, sampling ears at different growth stages from early dough to fully ripe. The amount of total and free fumonisin differed significantly between hybrids and increased significantl…

FusariumoxylipinsHealth Toxicology and MutagenesisCuticlelcsh:MedicineFood ContaminationFusarium verticillioidesmaizeFumonisinsZea maysArticlemycotoxinCell wallchemistry.chemical_compoundFusariumFumonisinBotanyMycotoxinsphingolipidsbiologylcsh:Rfood and beveragesRipeningLipidomebiology.organism_classificationSphingolipidFusarium verticillioides; maize; mycotoxin; oxylipins; sphingolipids; food contamination; food microbiology; fumonisins; fusarium; host-pathogen interactions; Oxylipins; sphingolipids; Zea mays; toxicology; health toxicology and mutagenesishealth toxicology and mutagenesischemistryBiochemistryHost-Pathogen InteractionsFood MicrobiologySettore AGR/12 - PATOLOGIA VEGETALE<i>Fusarium verticillioides</i>toxicologyToxins
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