0000000001096302

AUTHOR

F. Denat

showing 24 related works from this author

Nanoparticules d'or pour la radiothérapie guidée par imagerie Nanohybrides 10

2013

[CHIM] Chemical Sciences[CHIM]Chemical Sciences
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Multifunctional Gold Nanoparticles for Image-Guided Microbeam Radiation Therapy

2015

International audience; Owing to their large range of properties which can be accurately tuned by the chemical composition, the shape and the dimensions, multifunctional nanoparticles appear as promising candidates for imageguided therapy. For achieving this goal, we developed the synthesis of gold nanoparticles which are designed for combining multimodal imaging (magnetic resonance imaging (MRI), scintigraphy (SPECT), ultrasound imaging (echography) and X-ray imaging) and radiotherapy [1-5]. Ultrasmall gold nanoparticles were synthesized by reducing gold salt in presence of various highly hydrophilic dithiolated polyaminocarboxylate ligands (linear (DTDTPA) and macrocyclic (TADOTA, TADOTAG…

[PHYS.PHYS.PHYS-MED-PH] Physics [physics]/Physics [physics]/Medical Physics [physics.med-ph][SDV.CAN] Life Sciences [q-bio]/Cancer[ PHYS.PHYS.PHYS-MED-PH ] Physics [physics]/Physics [physics]/Medical Physics [physics.med-ph][PHYS.PHYS.PHYS-MED-PH]Physics [physics]/Physics [physics]/Medical Physics [physics.med-ph][SDV.CAN]Life Sciences [q-bio]/Cancer[ SDV.CAN ] Life Sciences [q-bio]/Cancer
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Theranostic gadolinium-based nanoparticles AGuIX®: in vivo imaging and safety evaluation

2015

International audience; IntroductionA new efficient type of gadolinium (Gd)-based theranostic agent (AGuIX®) has recently been developed for MRI-guided radiotherapy.1 These nanoparticles consist of a polysiloxane network surrounded by Gd chelates. Nanoparticles, which contain high-Z contrast agents such as Gd-based nanoparticles, increase the sensitivity of the tumor to radiation. Owing to their small size (3 +/- 0.1 nm), AGuIX® typically exhibit biodistributions that are almost ideal for diagnostic and therapeutic purposes.2 Multi-imaging properties and safety evaluation of the Gd-based nanoparticles have been investigated before their clinical transfer. MethodsGd-based nanoparticles have …

[SDV.IB.IMA] Life Sciences [q-bio]/Bioengineering/Imaging[SDV.CAN] Life Sciences [q-bio]/Cancer[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging[SDV.CAN]Life Sciences [q-bio]/Cancer[ SDV.IB.IMA ] Life Sciences [q-bio]/Bioengineering/Imaging[ SDV.CAN ] Life Sciences [q-bio]/Cancer
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Design and synthesis of multifunctional gold nanoparticles for image-guided therapy EMIM 2013

2013

[SDV.CAN] Life Sciences [q-bio]/Cancer[CHIM] Chemical Sciences[CHIM]Chemical Sciences[SDV.CAN]Life Sciences [q-bio]/Cancer
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CCDC 749976: Experimental Crystal Structure Determination

2010

Related Article: Y.Rousselin, N.Sok, F.Boschetti, R.Guilard, F.Denat|2010|Eur.J.Org.Chem.|2010|1688|doi:10.1002/ejoc.200901183

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters15-Phenyl-1481114-pentaazabicyclo[10.3.1]hexadecaneExperimental 3D Coordinates
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CCDC 749974: Experimental Crystal Structure Determination

2010

Related Article: Y.Rousselin, N.Sok, F.Boschetti, R.Guilard, F.Denat|2010|Eur.J.Org.Chem.|2010|1688|doi:10.1002/ejoc.200901183

Space GroupCrystallography1-(14710-Tetraazacyclotridecan-5-yl)methanamineCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 885458: Experimental Crystal Structure Determination

2013

Related Article: L.Stefan, B.Bertrand, P.Richard, P.Le Gendre, F.Denat, M.Picquet, D.Monchaud|2012|ChemBioChem|13|1905|doi:10.1002/cbic.201200396

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parametersbis(1379-tetramethyl-26-dioxo-236789-hexahydro-1H-purin-8-ylidene)-gold(i) tetrafluoroborateExperimental 3D Coordinates
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CCDC 619210: Experimental Crystal Structure Determination

2007

Related Article: F.Chaux, F.Denat, E.Espinosa, R.Guilard|2006|Chem.Commun.||5054|doi:10.1039/b612293k

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(17-(11'-Oxybis(2-methylenebenzene))-14710-tetra-azacyclododecane-NN'N''N'''O)-copper(ii) diperchlorateExperimental 3D Coordinates
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CCDC 787307: Experimental Crystal Structure Determination

2011

Related Article: C.Bazzicalupi, A.Bencini, S.Ciattini, F.Denat, P.Desogere, C.Goze, I.Matera, B.Valtancoli|2010|Dalton Trans.|39|11643|doi:10.1039/c0dt00948b

Space GroupCrystallographyCrystal System(10-(17-(22'-(Diphenyl ether)dimethyl))-4-azonia-1710-diaza-cyclododecane)-trichloro-zinc(ii)Crystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 902372: Experimental Crystal Structure Determination

2013

Related Article: P.Desogere,C.Bernhard,C.Goze,M.-J.Penouilh,Y.Rousselin,F.Denat|2013|Eur.J.Org.Chem.|2013|1538|doi:10.1002/ejoc.201201337

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates2a-Benzyl-1-(((t-butoxycarbonyl)amino)methyl)decahydro-5H-4a7a9a-triaza-2a-azoniacyclopenta[cd]phenalene bromide acetonitrile solvate
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CCDC 787306: Experimental Crystal Structure Determination

2011

Related Article: C.Bazzicalupi, A.Bencini, S.Ciattini, F.Denat, P.Desogere, C.Goze, I.Matera, B.Valtancoli|2010|Dalton Trans.|39|11643|doi:10.1039/c0dt00948b

Space GroupCrystallography17-(22'-(Diphenyl ether)dimethyl)-410-diazonia-17-diaza-cyclododecane tetrachloro-zinc(ii) monohydrateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 785489: Experimental Crystal Structure Determination

2010

Related Article: C.Bernhard, C.Goze, Y.Rousselin, F.Denat|2010|Chem.Commun.|46|8267|doi:10.1039/c0cc02749a

Space GroupCrystallographyN-(2-Aminoethyl)-N^alpha^-(4-(28-diethyl-55-difluoro-1379-tetramethyl-5H-4lambda^5^5lambda^5^-dipyrrolo[12-c:2'1'-f][132]diazaborinin-10-yl)benzoyl)-4-nitrophenylalaninamide dichloromethane solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 727679: Experimental Crystal Structure Determination

2010

Related Article: F.Denat, Y.A.Diaz-Fernandez, P.Pallavicini, L.Pasotti, Y.Rousselin, N.Sok|2009|Dalton Trans.||6751|doi:10.1039/b907289f

Space GroupCrystallographycatena-((mu2-1-(14710-Tetra-azacyclotridecan-5-yl)methylamine)-copper(ii) bis(trifluoromethanesulfonate) acetonitrile solvate)Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 787305: Experimental Crystal Structure Determination

2011

Related Article: C.Bazzicalupi, A.Bencini, S.Ciattini, F.Denat, P.Desogere, C.Goze, I.Matera, B.Valtancoli|2010|Dalton Trans.|39|11643|doi:10.1039/c0dt00948b

17-(22'-(Diphenyl ether)dimethyl)-410-diazonia-17-diaza-cyclododecane diperchlorateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 749975: Experimental Crystal Structure Determination

2010

Related Article: Y.Rousselin, N.Sok, F.Boschetti, R.Guilard, F.Denat|2010|Eur.J.Org.Chem.|2010|1688|doi:10.1002/ejoc.200901183

Space GroupCrystallography14-(9-Anthryl)-1471013-pentaazabicyclo[9.3.1]pentadecaneCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 902371: Experimental Crystal Structure Determination

2013

Related Article: P.Desogere,C.Bernhard,C.Goze,M.-J.Penouilh,Y.Rousselin,F.Denat|2013|Eur.J.Org.Chem.|2013|1538|doi:10.1002/ejoc.201201337

Space GroupCrystallography2a7a-Dibenzyl-1-cyanodecahydro-5H-4a9a-diaza-2a7a-diazoniacyclopenta[cd]phenalene dibromide trihydrateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 749973: Experimental Crystal Structure Determination

2010

Related Article: Y.Rousselin, N.Sok, F.Boschetti, R.Guilard, F.Denat|2010|Eur.J.Org.Chem.|2010|1688|doi:10.1002/ejoc.200901183

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters2-(Ammoniomethyl)-14710-tetraazoniacyclododecane pentachloride hemihydrateExperimental 3D Coordinates
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CCDC 787308: Experimental Crystal Structure Determination

2011

Related Article: C.Bazzicalupi, A.Bencini, S.Ciattini, F.Denat, P.Desogere, C.Goze, I.Matera, B.Valtancoli|2010|Dalton Trans.|39|11643|doi:10.1039/c0dt00948b

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(17-(dibenzofuran-18-diyldimethyl)-14710-tetraza-cyclododecane)-copper(ii) bis(hexafluorophosphate) acetonitrile solvateExperimental 3D Coordinates
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CCDC 749972: Experimental Crystal Structure Determination

2010

Related Article: Y.Rousselin, N.Sok, F.Boschetti, R.Guilard, F.Denat|2010|Eur.J.Org.Chem.|2010|1688|doi:10.1002/ejoc.200901183

Space GroupCrystallography9b9c-Dimethyldecahydro-5H-2a4a7a9a-tetraazacyclopenta[cd]phenalene-1-carbonitrileCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 902370: Experimental Crystal Structure Determination

2013

Related Article: P.Desogere,C.Bernhard,C.Goze,M.-J.Penouilh,Y.Rousselin,F.Denat|2013|Eur.J.Org.Chem.|2013|1538|doi:10.1002/ejoc.201201337

Space GroupCrystallography2a-Benzyl-1-cyanodecahydro-5H-4a7a9a-triaza-2a-azoniacyclopenta[cd]phenalene bromide methanol solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 619209: Experimental Crystal Structure Determination

2007

Related Article: F.Chaux, F.Denat, E.Espinosa, R.Guilard|2006|Chem.Commun.||5054|doi:10.1039/b612293k

Space GroupCrystallography17-bis(Ferrocenylmethyl)-14710-tetra-azacyclododecaneCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 749971: Experimental Crystal Structure Determination

2010

Related Article: Y.Rousselin, N.Sok, F.Boschetti, R.Guilard, F.Denat|2010|Eur.J.Org.Chem.|2010|1688|doi:10.1002/ejoc.200901183

8b8c-Dimethyldecahydro-2a4a6a8a-tetraazacyclopenta[fg]acenaphthylene-1-carbonitrileSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 750763: Experimental Crystal Structure Determination

2009

Related Article: Y.Rousselin, F.Denat, B.Lebeau, A.Walcarius|2009|Acta Crystallogr.,Sect.E:Struct.Rep.Online|65|o2531|doi:10.1107/S1600536809038112

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters18-bis[3-(triethoxysilyl)propyl]-411-diaza-18-diazoniatricyclo[9.3.1.1^48^]hexadecane diiodideExperimental 3D Coordinates
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CCDC 787304: Experimental Crystal Structure Determination

2011

Related Article: C.Bazzicalupi, A.Bencini, S.Ciattini, F.Denat, P.Desogere, C.Goze, I.Matera, B.Valtancoli|2010|Dalton Trans.|39|11643|doi:10.1039/c0dt00948b

Space GroupCrystallographyCrystal System17-(Dibenzofuran-18-diyldimethyl)-4-azonia-1710-triaza-cyclododecane 17-(dibenzofuran-18-diyldimethyl)-14710-tetraza-cyclododecane perchlorate hydrateCrystal StructureCell ParametersExperimental 3D Coordinates
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