0000000001099276

AUTHOR

Howard C. Thomas

showing 2 related works from this author

Biological standards for hepatitis B virus assays.

1992

Hepatitis B virusImmunoblottingBiologymedicine.disease_causePolymerase Chain ReactionVirusSerologylaw.inventionlawmedicineHumansHepatitis B AntibodiesPolymerase chain reactionHepatitis B virusHepatologyNucleic Acid HybridizationHepatitis BReference Standardsbiology.organism_classificationmedicine.diseaseHepatitis BVirologyIn vitroHepadnaviridaeDNA ViralViral diseaseJournal of hepatology
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Effectiveness of interferon alfa on incidence of hepatocellular carcinoma and decompensation in cirrhosis type C

1997

Background/Aims: The role of interferon alfa treatment in improving morbidity endpoints in patients with chronic hepatitis C infection is currently under debate. The aim of this study was to evaluate the effectiveness of interferon in preventing hepatocellular carcinoma and decompensation in cirrhosis type C. Methods: A retrospective cohort study was carried out on 329 consecutive Caucasian patients with cirrhosis followed for a mean period of 5 years at seven tertiary care university hospitals. Inclusion criteria were biopsy-proven cirrhosis, anti-HCV positivity, abnormal serum aminotransferase levels and absence of complications of cirrhosis. Results: The yearly incidence of hepatocellula…

medicine.medical_specialtyCirrhosisHepatologybusiness.industryIncidence (epidemiology)GastroenterologyAlpha interferonHepatitis Cmedicine.diseaseGastroenterologySurgeryLiver diseaseHepatocellular carcinomaInternal medicinemedicineDecompensationLiver functionbusinessInterferon alfamedicine.drug
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