0000000001101595

AUTHOR

Carlo Vancheri

showing 6 related works from this author

The Arg/Arg polymorphism of the ADRB2 is associated with the severity of allergic asthma

2016

ArginineGenotypeGlycineAdrenergicSettore MED/10 - Malattie Dell'Apparato RespiratorioArginine03 medical and health sciences0302 clinical medicineGenotypemedicineImmunology and AllergyHumans030212 general & internal medicineReceptorAdrenergic beta-2 Receptor AgonistsAsthmaPolymorphism Geneticbusiness.industryHomozygoteAllergic asthmaasthmamedicine.disease030228 respiratory systemImmunologyReceptors Adrenergic beta-2business
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Long-Term Domiciliary High-Flow Nasal Therapy in Patients with Bronchiectasis: A Preliminary Retrospective Observational Case-Control Study

2022

High-flow nasal therapy (HFNT) provides several pathophysiological benefits in chronic respiratory disorders. We aimed to evaluate the effectiveness of long-term HFNT in patients with bronchiectasis (BE). Methods: This is a retrospective bicentric case-control study of outpatients with BE on optimized medical treatment with a severe exacerbation requiring hospitalization in the previous year. Patients on long-term home HFNT (cases) and patients on optimized medical treatment alone (controls) were matched by age, sex, bronchiectasis severity index, and exacerbations in the previous year. Data on BE exacerbations, hospitalizations/year, mucus features, respiratory symptoms, and pulmonary func…

bronchiectasis; exacerbation; high-flow nasal cannula; high-flow nasal therapy; hospitalization; mucus;exacerbationbronchiectasis; exacerbation; high-flow nasal cannula; high-flow nasal therapy; hospitalization; mucushigh-flow nasal cannulahigh-flow nasal cannula; high-flow nasal therapy; bronchiectasis; mucus; exacerbation; hospitalizationbronchiectasismucusSettore MED/10 - Malattie dell'Apparato Respiratoriohigh-flow nasal therapyGeneral Medicinehospitalization
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Assessment of Lung Cancer Development in Idiopathic Pulmonary Fibrosis Patients Using Quantitative High-Resolution Computed Tomography:A Retrospectiv…

2020

Purpose The purpose of this study was to investigate histogram-based quantitative high-resolution computed tomography (HRCT) indexes in the assessment of lung cancer (LC) development in idiopathic pulmonary fibrosis (IPF) patients. Materials and methods From IPF databases of 2 national respiratory centers, we retrospectively studied patients with and without LC development-respectively, divided into Group A (n=16) and Group B (n=33). The extent of fibrotic disease was quantified on baseline and follow-up HRCT examinations using kurtosis, skewness, percentage of high attenuation area (HAA%), and percentage of fibrotic area (FA%). These indexes were compared between the 2 groups using the Man…

MalePulmonary and Respiratory MedicineHigh-resolution computed tomography030204 cardiovascular system & hematologylung neoplasmsSensitivity and Specificity030218 nuclear medicine & medical imaging03 medical and health sciencesIdiopathic pulmonary fibrosis0302 clinical medicineFibrosismedicineRetrospective analysisHumansRadiology Nuclear Medicine and imagingusual interstitial pneumoniaLung cancerLungmultidetectorAgedRetrospective StudiesAged 80 and overmedicine.diagnostic_testbusiness.industryRetrospective cohort studycomputed tomographyMiddle Agedmedicine.diseaseidiopathic pulmonary fibrosisDisease ProgressionMann–Whitney U testKurtosisFemaleTomography X-Ray ComputedNuclear medicinebusiness
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Suggestions for lung function testing in the context of COVID-19

2021

The 2019 coronavirus disease (COVID-19) pandemic is currently a challenge worldwide. Due to the characteristics of lung function tests, the risk of cross infection may be high between health care workers and patients. The role of lung function testing is well defined for the diagnosis of various diseases and conditions. Lung function tests are also indispensable in evaluating the response to medical treatment, in monitoring patient respiratory and systemic pathologies, and in evaluating preoperative risk in cardiothoracic and major abdominal surgeries. However, lung function testing represents a potential route for COVID-19 transmission, due to the aerosol generated during the procedures an…

Pulmonary and Respiratory Medicinemedicine.medical_specialtywarningsCoronavirus disease 2019 (COVID-19)Context (language use)DiseaseReview ArticleSettore MED/10 - Malattie Dell'Apparato RespiratorioPulmonary function testing03 medical and health sciences0302 clinical medicinePandemicHealth careMedicine030212 general & internal medicineIntensive care medicineLung functionbusiness.industryTransmission (medicine)COVID-19COVID-19; Indications; Lung function testing; warningsrespiratory systemLung function testing030228 respiratory systemIndications Lung function testing warnings COVID-19Indicationsbusiness
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Performance of Radiomics Features in the Quantification of Idiopathic Pulmonary Fibrosis from HRCT.

2020

Background: Our study assesses the diagnostic value of different features extracted from high resolution computed tomography (HRCT) images of patients with idiopathic pulmonary fibrosis. These features are investigated over a range of HRCT lung volume measurements (in Hounsfield Units) for which no prior study has yet been published. In particular, we provide a comparison of their diagnostic value at different Hounsfield Unit (HU) thresholds, including corresponding pulmonary functional tests. Methods: We consider thirty-two patients retrospectively for whom both HRCT examinations and spirometry tests were available. First, we analyse the HRCT histogram to extract quantitative lung fibrosis…

Spirometrymusculoskeletal diseasesHigh-resolution computed tomographyhigh resolution computed tomographyClinical Biochemistry-Article030218 nuclear medicine & medical imagingPulmonary function testing03 medical and health sciencesIdiopathic pulmonary fibrosis0302 clinical medicineRadiomicsHounsfield scalemedicineSettore ING-INF/05 - Sistemi Di Elaborazione Delle Informazionilcsh:R5-920Lungmedicine.diagnostic_testbusiness.industryLung fibrosisrespiratory systemmedicine.diseaseidiopathic pulmonary fibrosisrespiratory tract diseasesmedicine.anatomical_structure030228 respiratory systemradiomicslcsh:Medicine (General)businessNuclear medicineDiagnostics (Basel, Switzerland)
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Influence of Antisynthetase Antibodies Specificities on Antisynthetase Syndrome Clinical Spectrum Time Course

2019

Antisynthetase syndrome (ASSD) is a rare clinical condition that is characterized by the occurrence of a classic clinical triad, encompassing myositis, arthritis, and interstitial lung disease (ILD), along with specific autoantibodies that are addressed to different aminoacyl tRNA synthetases (ARS). Until now, it has been unknown whether the presence of a different ARS might affect the clinical presentation, evolution, and outcome of ASSD. In this study, we retrospectively recorded the time of onset, characteristics, clustering of triad findings, and survival of 828 ASSD patients (593 anti-Jo1, 95 anti-PL7, 84 anti-PL12, 38 anti-EJ, and 18 anti-OJ), referring to AENEAS (American and Europea…

medicine.medical_specialtyantisynthetase antibodies; antisynthetase syndrome; arthritis; interstitial lung disease; myositisantisynthetase syndrome; antisynthetase antibodies; arthritis; myositis; interstitial lung diseaseMedizinArthritislcsh:MedicineAntisynthetase syndromeInterstitial lung diseaseAntisynthetase syndromeArticleNO03 medical and health sciences0302 clinical medicineInternal medicinemedicineantisynthetase antibodiesantisynthetase antibodies antisynthetase syndrome arthritis interstitial lung disease myositisddc:610Myositis030203 arthritis & rheumatologyinterstitial lung diseaseAntisynthetase antibodiesbiologyMyositisbusiness.industryArthritislcsh:RInterstitial lung diseaseAutoantibodyGeneral Medicinemedicine.diseasearthriti030228 respiratory systemarthritisTime courseCohortbiology.proteinAntibodyantisynthetase syndromebusinessantisynthetase antibodiemyositis
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