Author: Benedict Petran

0000000001102357

AUTHOR

Benedict Petran

Syntheses of Trifluoroethylated N-Heterocycles from Vinyl Azides and Togni’s Reagent Involving 1,n-Hydrogen-Atom Transfer Reactions

2,2,2-Trifluoroethyl-substituted 3-oxazolines, 3-thiazolines, and 5,6-dihydro-2H-1,3-oxazines have been obtained by reacting substituted vinyl azides with a combination of Togni’s reagent and substoichiometric amounts of iron(II) chloride. The results of density functional theory calculations support the proposed mechanism involving 1,n-hydrogen-atom transfer reactions. peerReviewed

research product

CCDC 1983428: Experimental Crystal Structure Determination

Related Article: Steven Terhorst, Deo Prakash Tiwari, Daniela Meister, Benedict Petran, Kari Rissanen, Carsten Bolm|2020|Org.Lett.|22|4766|doi:10.1021/acs.orglett.0c01566

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