0000000001102358
AUTHOR
Steven Terhorst
Syntheses of Trifluoroethylated N-Heterocycles from Vinyl Azides and Togni’s Reagent Involving 1,n-Hydrogen-Atom Transfer Reactions
2,2,2-Trifluoroethyl-substituted 3-oxazolines, 3-thiazolines, and 5,6-dihydro-2H-1,3-oxazines have been obtained by reacting substituted vinyl azides with a combination of Togni’s reagent and substoichiometric amounts of iron(II) chloride. The results of density functional theory calculations support the proposed mechanism involving 1,n-hydrogen-atom transfer reactions. peerReviewed
CCDC 1983428: Experimental Crystal Structure Determination
Related Article: Steven Terhorst, Deo Prakash Tiwari, Daniela Meister, Benedict Petran, Kari Rissanen, Carsten Bolm|2020|Org.Lett.|22|4766|doi:10.1021/acs.orglett.0c01566