0000000001104052

AUTHOR

Meilin Qu

showing 8 related works from this author

Synthesis of Polycyclic Indolines by Utilizing a Reduction/Cyclization Cascade Reaction

2021

European journal of organic chemistry 2021(45), 6097-6101 (2021). doi:10.1002/ejoc.202101191

Reduction (complexity)Acid catalysisCascade reactionChemistryddc:540Organic ChemistryPhysical and Theoretical Chemistry540Combinatorial chemistryEuropean Journal of Organic Chemistry
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Cover Feature: Synthesis of Polycyclic Indolines by Utilizing a Reduction/Cyclization Cascade Reaction (Eur. J. Org. Chem. 45/2021)

2021

Reduction (complexity)Cascade reactionFeature synthesisComputational chemistryChemistryOrganic ChemistryCover (algebra)Physical and Theoretical ChemistryEuropean Journal of Organic Chemistry
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Synthesis of Polycyclic Indolines utilizing a reduction/cyclization cascade reaction

2021

Subsequent reduction and dearomatizing cyclization reactions open up an entry into the synthesis of novel N-fused polycyclic indolines. The dearomatizing cyclization as key step of the sequence proceeds well with Cu(OTf)2 or TfOH as catalyst. At elevated temperature reduction of nitro-substituted precursors with iron under acidic conditions affords a broad variety of polycyclic indolines directly in a two-step cascade reaction in good to excellent yields. Using the developed protocol, the alkaloids Tryptanthrin and Phaitanthrin C have been prepared. peerReviewed

kemiallinen synteesicyclizationkatalyysinitrogen heterocyclescascade reactionshapetus-pelkistysreaktioorgaaniset yhdisteetacid catalysisdearomatization
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CCDC 2080687: Experimental Crystal Structure Determination

2021

Related Article: Jingyu Zhang, Wei Xia, Meilin Qu, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Eur.J.Org.Chem.|2021|6097|doi:10.1002/ejoc.202101191

Space GroupCrystallographyCrystal System8-methoxy-5a-methyl-5a6-dihydroindolo[21-b]quinazolin-12(5H)-oneCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2080689: Experimental Crystal Structure Determination

2021

Related Article: Jingyu Zhang, Wei Xia, Meilin Qu, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Eur.J.Org.Chem.|2021|6097|doi:10.1002/ejoc.202101191

Space GroupCrystallographyCrystal SystemCrystal Structure8-chloro-5a-methyl-5a6-dihydroindolo[21-b]quinazolin-12(5H)-oneCell ParametersExperimental 3D Coordinates
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CCDC 2080691: Experimental Crystal Structure Determination

2021

Related Article: Jingyu Zhang, Wei Xia, Meilin Qu, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Eur.J.Org.Chem.|2021|6097|doi:10.1002/ejoc.202101191

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates5a-(4-chlorophenyl)-5a6-dihydroindolo[21-b]quinazolin-12(5H)-one
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CCDC 2080688: Experimental Crystal Structure Determination

2021

Related Article: Jingyu Zhang, Wei Xia, Meilin Qu, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Eur.J.Org.Chem.|2021|6097|doi:10.1002/ejoc.202101191

Space GroupCrystallography8-fluoro-5a-methyl-5a6-dihydroindolo[21-b]quinazolin-12(5H)-oneCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2080690: Experimental Crystal Structure Determination

2021

Related Article: Jingyu Zhang, Wei Xia, Meilin Qu, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Eur.J.Org.Chem.|2021|6097|doi:10.1002/ejoc.202101191

Space GroupCrystallography5a6-dimethyl-5a6-dihydroindolo[21-b]quinazolin-12(5H)-oneCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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