0000000001104830

AUTHOR

Guillaume Py

Jusqu’où réduire l’usage de pesticide sans dégrader la productivité et la rentabilité de l’exploitation ?

prod 2017-301 SPE EA GESTAD DOCT INRA; National audience; Le suivi des fermes du réseau Dephy, créé entre 2010 et 2012 dans le cadre du plan Écophyto, permet, d’ores et déjà, d’évaluer les possibilités de réduire la dépendance aux pesticides : – en analysant les pratiques actuelles (en comparant les exploitations entre elles) ; – mais également en simulant des évolutions sur des scénarios réalistes. L’analyse de 946 fermes du réseau travaillant en agriculture conventionnelle montre la complexité des liens entre indicateur de fréquence de traitement (IFT) global de l’exploitation (système de culture), la productivité (exprimée en énergie produite) et la rentabilité (marge semi-nette). Il en …

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Muscle resting and TGF-β inhibitor treatment prevent fatty infiltration following skeletal muscle injury

Background/Aims: Skeletal muscle injuries are the most common type of injury occurring in sports, and investigating skeletal muscle regeneration as well as understanding the related processes is an important aspect of the sports medicine field. The process of regeneration appears to be complex and precisely orchestrated, involving fibro-adipogenic progenitors (FAPs) which are a muscle-resident stem cell population that appears to play a major role in abnormal development of fibrotic tissue or intermuscular adipose tissue (IMAT). Our present study aims to investigate whether muscle resting or endurance exercise following muscle injury may change the behavior of FAPs and subsequently impact t…

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Evaluation of an Antioxidant and Anti-inflammatory Cocktail Against Human Hypoactivity-Induced Skeletal Muscle Deconditioning

International audience; Understanding the molecular pathways involved in the loss of skeletal muscle mass and function induced by muscle disuse is a crucial issue in the context of spaceflight as well as in the clinical field, and development of efficient countermeasures is needed. Recent studies have reported the importance of redox balance dysregulation as a major mechanism leading to muscle wasting. Our study aimed to evaluate the effects of an antioxidant/anti-inflammatory cocktail (741 mg of polyphenols, 138 mg of vitamin E, 80 mu g of selenium, and 2.1 g of omega-3) in the prevention of muscle deconditioning induced by long-term inactivity. The study consisted of 60 days of hypoactivi…

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