ENGINEERING OF p65(-1)-/- KNOCK-IN MOUSE, A NEW ALTERNATIVE SPLICED ISOFORM OF p65, A PROTEIN OF NF-KB COMPLEX.

COMPUTER MODEL OF ARTERIAL BIO-MECHANICS.EVALUATION OF RUPTURED ABDOMINAL AORTIC ANEURYSM WALL THROUGH FINITE ELEMENT ANALYSIS

Randomized double-blind placebo-controlled trial of acetyl-L-carnitine for ALS.

Our objective was to assess the effects of acetyl-L-carnitine (ALC) with riluzole on disability and mortality of amyotrophic lateral sclerosis (ALS). Definite/probable ALS patients, 40-70 years of age, duration 6-24 months, self-sufficient (i.e. able to swallow, cut food/handle utensils, and walk), and with forced vital capacity (FVC) > 80% entered a pilot double-blind, placebo-controlled, parallel group trial and were followed for 48 weeks. ALC or placebo 3 g/day was added to riluzole 100 mg/day. Primary endpoint: number of patients no longer self-sufficient. Secondary endpoints: changes in ALSFRS-R, MRC, FVC and McGill Quality of Life (QoL) scores. Analysis was made in the intention-to-tr…

ATRIAL NATRIURETIC FACTOR,BUT NOT OXYTOCIN, PRESENCE IN ATHEROSCLEROTIC PLAQUES OF HUMAN COMMON CAROTID

Identificazione e caratterizzazione funzionale di isoforme di p65 del complesso NF-kB

Clinical effects of different montages of Transcranial Direct Current Stimulation (tDCS) in patients with Parkinson’s Disease

Background: Parkinson’s disease (PD) is characterized by motor deficits which may not completely respond to the dopaminergic therapy, thus posing a therapeutic challenge. Non-invasive brain stimulation techniques such as transcranial direct current stimulation (tDCS) have shown promising results as possible alternative of treatment in different neurological disorders including PD. The therapeutic effect of tDCS, which may increase (anodal currents) or decrease (cathodal currents) the cortical excitability level, likely relies on modulation of cortico-subcortical interactions and abnormal patterns of cortical activation. Objective: To investigate safety and therapeutic potential of different…

Atrial natriuretic factor, but not oxytocin, is present in atherosclerotic plaques of human common carotid arteries: an immunohistochemical in vivo study.

Atrial natriuretic factor,but non oxytocin, presence in atherosclerotic plaques of human common carotid arteries