Author: International Sheep Genomics Consortium

0000000001105822

AUTHOR

International Sheep Genomics Consortium

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Genome wide linkage disequilibrium and genetic structure in Sicilian dairy sheep breeds

2014

Background The recent availability of sheep genome-wide SNP panels allows providing background information concerning genome structure in domestic animals. The aim of this work was to investigate the patterns of linkage disequilibrium (LD), the genetic diversity and population structure in Valle del Belice, Comisana, and Pinzirita dairy sheep breeds using the Illumina Ovine SNP50K Genotyping array. Results Average r2 between adjacent SNPs across all chromosomes was 0.155 ± 0.204 for Valle del Belice, 0.156 ± 0.208 for Comisana, and 0.128 ± 0.188 for Pinzirita breeds, and some variations in LD value across chromosomes were observed, in particular for Valle del Belice and Comisana breeds. Ave…

Linkage disequilibriumSicilian sheep breedsPopulationSingle-nucleotide polymorphismBiologyBreedingPolymorphism Single NucleotideLinkage DisequilibriumSettore AGR/17 - Zootecnica Generale E Miglioramento GeneticoGenome structureOvineSNP50K BeadChip Sicilian sheep breeds Linkage Disequilibrium genome structureGeneticsAnimalsGenetics(clinical)educationSicilyGenetics (clinical)PhylogenySheep DomesticGenetic associationGeneticsGenetic diversityeducation.field_of_studyPrincipal Component AnalysisModels GeneticOvineSNP50K BeadChipBayes TheoremBreedGenetic structureInbreedingGenome-Wide Association StudyResearch Article

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