0000000001106599

AUTHOR

S Coelho Leal

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Oral health effects of botulinum toxin treatment for drooling:a systematic review

2020

Background Drooling is a major morbidity in several neurological diseases. Intraglandular botulinum neurotoxin (BoNT) injections have been used to manage this condition. However, by decreasing salivary flow, BoNT injections may result in an increased risk of caries and other oral adverse effects. In this study, we aimed to assess whether, in patients with drooling, intraglandular BoNT injections are associated with increased dental caries development, modifications on salivary composition (oral pH, buffering capacity and osmolality) and cariogenic bacterial load. Material and Methods We performed a systematic review, searching PubMed, CENTRAL, Web of Science, and Scopus for all experimental…

medicine.medical_specialtyMEDLINEOral HealthReviewOral healthDental CariesDroolinglaw.inventionameloblastomaRandomized controlled triallawInternal medicinemedicineHumansBotulinum Toxins Type AAdverse effectGeneral DentistryUNESCO:CIENCIAS MÉDICASbusiness.industryCerebral Palsyodontogenic tumorSialorrheaMedically compromised patients in Dentistryameloblastoma recurrenceBotulinum toxinOtorhinolaryngologyNeuromuscular AgentsSurgeryObservational studymedicine.symptombusinessoral pathologyBiomedical sciencesmedicine.drug
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