0000000001110262

AUTHOR

Elisa Tirtei

showing 3 related works from this author

Musculoskeletal manifestations of childhood cancer and differential diagnosis with juvenile idiopathic arthritis (ONCOREUM): a multicentre, cross-sec…

2021

Summary Background Presenting symptoms of childhood cancers might mimic those of rheumatic diseases. However, the evidence available to guide differential diagnosis remains scarce. Preventing wrong or delayed diagnosis is therefore important to avoid incorrect administration of glucocorticoid or immunosuppressive therapy and worsening of prognosis. As such, we aimed to assess the prevalence and characteristics of presenting musculoskeletal manifestations in patients at cancer onset and to identify the factors that differentiate childhood malignancies with arthropathy from juvenile idiopathic arthritis. Methods We did a multicentre, cross-sectional study at 25 paediatric haemato-oncology cen…

medicine.medical_specialtybusiness.industryImmunologyArthritisCancerOdds ratioMusculoskeletal manifestationJuvenile idiopathic arthritismedicine.diseaseHistiocytosisRheumatologySettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICAPrednisoneInternal medicineJoint painArthropathyMusculoskeletal manifestations childhood cancer juvenile idiopathic arthritismedicinechildhood cancerImmunology and AllergyDifferential diagnosismedicine.symptombusinessmedicine.drug
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Stage 4 s neuroblastoma: features, management and outcome of 268 cases from the Italian Neuroblastoma Registry

2019

Background Infants diagnosed with stage 4 s neuroblastoma commonly experience spontaneous disease regression, with few succumbing without response to therapy. We analyzed a large cohort of such infants enrolled in the Italian Neuroblastoma Registry to detect changes over time in presenting features, treatment and outcome. Methods Of 3355 subjects aged 0–18 years with previously untreated neuroblastoma diagnosed between 1979 and 2013, a total of 280 infants (8.3%) had stage 4 s characteristics, 268 of whom were eligible for analyses. Three treatment eras were identified on the basis of based diagnostic and chemotherapy adopted. Group 1 patients received upfront chemotherapy; Group 2 and 3 pa…

Malemedicine.medical_specialtyMultivariate analysisAdolescentmedicine.medical_treatmentLiver transplantationPrognostic factorsPediatricsCohort Studies03 medical and health sciencesNeuroblastoma0302 clinical medicineStage 4 s030225 pediatricsInternal medicineNeuroblastomamedicineHumansRegistries030212 general & internal medicineElevated ldhStage (cooking)Risk factorChildMale genderStage 4 sNeoplasm StagingChemotherapybusiness.industryResearchInfant Newbornlcsh:RJ1-570Infantlcsh:PediatricsPerinatology and Child Healthmedicine.diseaseSurvival RateInfants; Neuroblastoma; Prognostic factors; Stage 4 s; Pediatrics Perinatology and Child HealthItalyChild PreschoolFemalebusinessInfantsItalian Journal of Pediatrics
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Additional file 1: of Stage 4 s neuroblastoma: features, management and outcome of 268 cases from the Italian Neuroblastoma Registry

2019

Table S1. Outlines of therapy for stage 4 s neuroblastoma patients (DOCX 16 kb)

neoplasms
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