0000000001115132

AUTHOR

Sa Stilo

showing 3 related works from this author

Interaction between cannabis consumption and childhood abuse in psychotic disorders:preliminary findings on the role of different patterns of cannabi…

2014

Aim: Several studies have suggested that lifetime cannabis consumption and childhood abuse synergistically contribute to the risk for psychotic disorders. This study aimed to extend existing findings regarding an additive interaction between childhood abuse and lifetime cannabis use by investigating the moderating role of type and frequency of cannabis use. Methods: Up to 231 individuals presenting for the first time to mental health services with psychotic disorders and 214 unaffected population controls from South London, United Kingdom, were recruited as part of the Genetics and Psychosis study. Information about history of cannabis use was collected using the Cannabis Experiences Questi…

AdultMalecannabischildhood traumaAdult Survivors of Child AbuseinteractionMarijuana SmokingComorbiditymarijuana smokingYoung Adultcannabis childhood trauma first-episode psychosis interaction marijuana smokingPsychotic DisordersRisk FactorsSurveys and QuestionnairesSettore M-PSI/08 - Psicologia ClinicaLondonSettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.HumansFemalefirst-episode psychosisCannabis childhood trauma first-episode psychosis interaction marijuana smokingSettore MED/25 - Psichiatria
researchProduct

First-Episode Psychosis Patients Who Deteriorated in the Premorbid Period Do Not Have Higher Polygenic Risk Scores Than Others: A Cluster Analysis of…

2023

Abstract Cluster studies identified a subgroup of patients with psychosis whose premorbid adjustment deteriorates before the onset, which may reflect variation in genetic influence. However, other studies reported a complex relationship between distinctive patterns of cannabis use and cognitive and premorbid impairment that is worthy of consideration. We examined whether: (1) premorbid social functioning (PSF) and premorbid academic functioning (PAF) in childhood and adolescence and current intellectual quotient (IQ) define different clusters in 802 first-episode of psychosis (FEP) patients; resulting clusters vary in (2) polygenic risk scores (PRSs) for schizophrenia (SCZ_PRS), bipolar dis…

cannabiscannabiAdolescentBIPOLAR DISORDERADJUSTMENTGENE-ENVIRONMENT INTERACTIONSCLASSIFICATIONbipolarschizophreniaPsychiatry and Mental healthPsychotic DisordersRisk FactorsIQONSETpremorbidschizophrenia.HumansCluster AnalysisGENOME-WIDE ASSOCIATIONTRAJECTORIESdeteriorationSchizophrenia Bulletin
researchProduct

THE ROLE OF CHILDHOOD TRAUMA AND COGNITIVE DEFICIT IN MODERATING THE RISK FOR PSYCHOTIC DISORDERS: A COMPARISON BETWEEN PALERMO AND SOUTH-EAST LONDON…

2011

childhood trauma; cognitive deficit; psychosischildhood traumapsychosiscognitive deficit
researchProduct