0000000001115565
AUTHOR
Benjamin Hoy
Complex Cellular Responses of Helicobacter pylori-Colonized Gastric Adenocarcinoma Cells ▿
ABSTRACT Helicobacter pylori is an important class I carcinogen that persistently infects the human gastric mucosa to induce gastritis, gastric ulceration, and gastric cancer. H. pylori pathogenesis strongly depends on pathogenic factors, such as VacA (vacuolating cytotoxin A) or a specialized type IV secretion system (T4SS), which injects the oncoprotein CagA (cytotoxin-associated gene A product) into the host cell. Since access to primary gastric epithelial cells is limited, many studies on the complex cellular and molecular mechanisms of H. pylori were performed in immortalized epithelial cells originating from individual human adenocarcinomas. The aim of our study was a comparative anal…
Correction for Schneider et al., Complex Cellular Responses of Helicobacter pylori-Colonized Gastric Adenocarcinoma Cells
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