S153. WHERE IS THE ABNORMAL BRAIN ACTIVITY IN FIRST EPISODE PSYCHOSIS?

Abstract Background Recent review about functional magnetic resonance imaging (fMRI) in first episode psychosis (FEP) concluded that there is an abnormal connectivity involving the frontal temporal pathway similar to found in chronic schizophrenia (Mwansisya et al., 2017). Besides, thalamic circuits were also altered in chronic schizophrenia patients (Li et al., 2017). The present work gives a wider review of studies using functional magnetic resonance imaging techniques (fMRI) on first-episode psychotic patients, specifically focus on the main areas involved. Methods The review was made in accordance with the PRISMA guidelines (Moher et al., 2009). For each study, the following factors wer…