0000000001119366

AUTHOR

Sally Dawson

showing 2 related works from this author

Genome-wide association analysis on normal hearing function identifies PCDH20 and SLC28A3 as candidates for hearing function and loss.

2015

Hearing loss and individual differences in normal hearing both have a substantial genetic basis. Although many new genes contributing to deafness have been identified, very little is known about genes/variants modulating the normal range of hearing ability. To fill this gap, we performed a two-stage meta-analysis on hearing thresholds (tested at 0.25, 0.5, 1, 2, 4, 8 kHz) and on pure-tone averages (low-, medium-and high-frequency thresholds grouped) in several isolated populations from Italy and Central Asia (total N = 2636). Here, we detected two genome-wide significant loci close to PCDH20 and SLC28A3 (top hits: rs78043697, P = 4.71E-10 and rs7032430, P = 2.39E-09, respectively). For both…

Genome-wide association studieLOCICOMMON DISEASESNerve Tissue ProteinsVARIANTSSUSCEPTIBILITYDeafnessGenome-wide association studiesMiceHearingGenome-wide association studies; normal hearing function; PCDH20; SLC28A3PCDH20SLC28A3otorhinolaryngologic diseasesAnimalsHumansGenetic Predisposition to DiseaseMETAANALYSISHair Cells Auditory InnerSequence Analysis RNAAssociation Studies ArticlesMembrane Transport ProteinsLOCALIZATIONCadherinsTRANSPORTER-3ProtocadherinsGENOTYPEMYOSIN-VIIAItalyAsia Centralnormal hearing function3111 BiomedicineGenome-Wide Association StudyHuman molecular genetics
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The Hunt for New Physics at the Large Hadron Collider

2010

233 páginas.-- AHEP Group: et al..-- El Pdf del artículo es la versión pre-print: arXiv.1001.2693v1.-- Trabajo presentado al "The International Workshop on Beyond the Standard Model Physics and LHC Signatures (BSM-LHC) celebrado en Boston (USA) del 2 al 4 de junio de 2009.

Nuclear and High Energy PhysicsParticle physicsCold dark matterPhysics::Instrumentation and DetectorsPhysics beyond the Standard ModelFOS: Physical sciencesRANDALL-SUNDRUM MODEL01 natural sciencesHigh Energy Physics - Phenomenology (hep-ph)R-PARITY BREAKING0103 physical sciencesHigh Energy PhysicsANOMALOUS MAGNETIC-MOMENT010306 general physicsParticle Physics - PhenomenologyPhysicsEXPLICIT CP VIOLATIONDARK-MATTER DETECTIONLarge Hadron Collider010308 nuclear & particles physicsPhysicsElectroweak interactionHigh Energy Physics::PhenomenologyFísicaRENORMALIZATION-GROUP EQUATIONSHierarchy problemSupersymmetryAtomic and Molecular Physics and OpticsGRAND UNIFIED THEORIESSUPERSYMMETRIC STANDARD MODELHidden sectorExtra dimensionsHigh Energy Physics - PhenomenologyMINIMAL FLAVOR VIOLATION[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]PhenomenologyHigh Energy Physics::ExperimentHIGGS-BOSON PRODUCTION
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