0000000001122746

AUTHOR

Florian Chain

0000-0001-8787-3311

showing 2 related works from this author

Drying process strongly affects probiotics viability and functionalities

2015

International audience; Probiotic formulations are widely used and are proposed to have a variety of beneficial effects, depending on the probiotic strains present in the product. The impact of drying processes on the viability of probiotics is well documented. However, the impact of these processes on probiotics functionality remains unclear. In this work, we investigated variations in seven different bacterial markers after various desiccation processes. Markers were composed of four different viability evaluation (combining two growth abilities and two cytometric measurements) and in three in vitro functionalities: stimulation of IL-10 and IL-12 production by PBMCs (immunomodulation) and…

ved/biology.organism_classification_rank.speciesBioengineeringApplied Microbiology and Biotechnologylaw.invention03 medical and health sciencesProbioticlawLactobacillus[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringDesiccationFunctionality030304 developmental biologyBifidobacteriumDrying2. Zero hunger0303 health sciencesBifidobacterium bifidumMicrobial ViabilityMicrobial Viabilitybiology030306 microbiologyved/biologyProbioticsGeneral Medicinebiology.organism_classificationLactobacillusProcessBiochemistryViabilityBifidobacteriumDesiccationBacteriaLactobacillus plantarumBiotechnology
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Age-Related Changes in the Gut Microbiota Modify Brain Lipid Composition

2020

PMCID: PMC6970973; International audience; Understanding the molecular mechanisms underlying the changes observed during aging is a prerequisite to design strategies to prevent age-related diseases. Aging is associated with metabolic changes, including alteration in the brain lipid metabolism. These alterations may contribute to the development of pathophysiological conditions. Modifications in the gut microbiota composition are also observed during aging. As communication axes exist between the gut microbiota and the brain and knowing that microbiota influences the host metabolism, we speculated on whether age-associated modifications in the gut microbiota could be involved in the lipid ch…

Fatty Acid DesaturasesMale0301 basic medicinelcsh:QR1-502Gene ExpressionGut floralcsh:MicrobiologyFatty Acids MonounsaturatedMiceCellular and Infection MicrobiologyAging brain[SDV.BDD]Life Sciences [q-bio]/Development BiologyOriginal Researchchemistry.chemical_classificationFatty AcidsAge FactorsBrainLipidscortexInfectious DiseasesFatty Acids Unsaturated[SDV.IMM]Life Sciences [q-bio]/Immunologylipids (amino acids peptides and proteins)SphingomyelinStearoyl-CoA DesaturasePolyunsaturated fatty acidMicrobiology (medical)medicine.medical_specialty[SDV.IMM] Life Sciences [q-bio]/ImmunologyFatty Acid ElongasesFADS1FADS2030106 microbiologyImmunologyBiologyliverdigestive systemMicrobiology03 medical and health scienceslipidInternal medicine[SDV.BDD] Life Sciences [q-bio]/Development BiologymedicinemicrobiotaAnimalsGerm-Free LifephospholipidagingFatty acidcholesterolLipid Metabolismbiology.organism_classificationGastrointestinal MicrobiomeTransplantation[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition030104 developmental biologyEndocrinologychemistryfatty acid[SDV.AEN]Life Sciences [q-bio]/Food and NutritionFrontiers in Cellular and Infection Microbiology
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