0000000001130370
AUTHOR
Florian Koensgen
Exploring of odor blending in odorant mixtures by a pharmacophore approach
The first step of odor perception is an interaction between odorants and olfactory receptors (ORs) [1]. It is now accepted that the main strategy used by Humans to perceive thousands of odors results from a combinatorial coding [2]. Moreover, odors we perceived in our environment are mainly the result of mixtures of odorants; however, the processes involved remain poorly understood [3]. In previous studies performed in the CSGA of Dijon[4, 5], the perception of a mixture of specific proportions of ethyl isobutyrate (Et-iB, strawberry-like odor) and ethyl maltol (Et-M, caramel-like odor) was investigated in comparison with a reference (allyl hexanoate, Al-H, pineapple-like odor) chosen to ev…
Pharmacophore study of a blending six-component odor mixture
The first step of odor perception is an interaction between odorants and olfactory receptors [1]. The corresponding transduced olfactory signals, conveyed by olfactory sensory neurons, are then processed by the brain [2]. It is now accepted that the main strategy used to discriminate thousands of odors results from a combinatorial coding [3]. Moreover, odors perceived in our environment are mainly the result of mixtures of odorants; however, the specific mechanisms involved in their processing remain poorly understood [4]. In previous studies performed in the CSGA of Dijon [5-7], we investigated the perception of a mixture of 6 components: vanillin, oxanone (4-(4-hydroxyphenyl)butan-2-one),…