Author: Tobias G.j. Abt

0000000001131437

AUTHOR

Tobias G.j. Abt

showing 1 related works from this author

Profile of the Immune and Inflammatory Response in Individuals With Prediabetes and Type 2 Diabetes.

2015

OBJECTIVE The inflammatory and immune systems are altered in type 2 diabetes. Here, the aim was to profile the immune and inflammatory response in subjects with prediabetes and diabetes in a large population-representative sample. RESEARCH DESIGN AND METHODS In total, 15,010 individuals were analyzed from the population-based Gutenberg Health Study. Glucose status was classified according to HbA1c concentration and history of diagnosis. All samples were analyzed for white blood cells (WBCs), granulocytes, lymphocytes, monocytes, platelets, C-reactive protein (CRP), albumin, fibrinogen, and hematocrit. Interleukin-18 (IL-18), IL-1 receptor antagonist (IL-1RA), and neopterin concentrations w…

AdultMaleEndocrinology Diabetes and MetabolismPopulationType 2 diabetesComorbidityHematocritFibrinogenPrediabetic Statechemistry.chemical_compoundImmune systemRisk FactorsDiabetes mellitusInternal MedicinemedicineHumansPrediabeteseducationAgedAdvanced and Specialized NursingInflammationeducation.field_of_studymedicine.diagnostic_testbusiness.industryImmunityNeopterinMiddle Agedmedicine.diseaseC-Reactive ProteinchemistryDiabetes Mellitus Type 2Cardiovascular DiseasesImmunologyDisease ProgressionFemalebusinessBiomarkersmedicine.drugDiabetes care

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