0000000001133602

AUTHOR

Didier Trotier

showing 6 related works from this author

Taste receptors to L-glutamate

2007

National audience

[SDV] Life Sciences [q-bio]TASTE RECEPTORGLUTAMATE[SPI.GPROC] Engineering Sciences [physics]/Chemical and Process Engineering[SDV]Life Sciences [q-bio][SDV.IDA]Life Sciences [q-bio]/Food engineering[INFO]Computer Science [cs][SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering[INFO] Computer Science [cs][SDV.IDA] Life Sciences [q-bio]/Food engineeringINTER-INDIVIDUAL DIFFERENCESComputingMilieux_MISCELLANEOUS
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Tas1R1-Tas1R3 taste receptor variants in human fungiform papillae.

2009

International audience; Monosodium glutamate as well as metabotropic and ionotropic glutamate receptor agonists have been reported to be perceived as umami by humans. In spite of the fact that Tas1R1-Tas1R3 has been shown to mediate most of the glutamate taste sensation in mice other candidate receptors have been put forward for which a clear role in detection is still lacking. This work was aimed at investigating the molecular determinants underlying umami taste detection in humans. First, we show evidence supporting expression of Tas1R1 and Tas1R3 but not mGluRs in the fungiform papillae of several individuals. Next, we report a number of naturally occurring l-glutamate taste receptor var…

AdultMaleTasteTASTE RECEPTORSGlutamic AcidSNPFUNGIFORM PAPILLAEUmamiBiologyLigandsReceptors Metabotropic GlutamatePolymorphism Single NucleotideReceptors G-Protein-CoupledTAS1R103 medical and health sciencesGLUTAMATE0302 clinical medicineTAS1R3Allosteric RegulationTongueTaste receptorHumansProtein IsoformsMSG030304 developmental biologyAgedGenetics0303 health sciencesBinding SitesGeneral Neuroscience[SCCO.NEUR]Cognitive science/NeuroscienceGenetic VariationHUMANMiddle AgedTaste BudsProtein Structure TertiaryTAS2R38BiochemistryTasteTaste Threshold[ SCCO.NEUR ] Cognitive science/NeuroscienceMetabotropic glutamate receptor 1Ionotropic glutamate receptorFemaleUNAMI030217 neurology & neurosurgery
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Nonsynonymous SNPs in human tas1r1, tas1r3, mGluR1 and individual taste sensitivity to glutamate

2009

 ; Nonsynonymous SNPs in human tas1r1, tas1r3, mGluR1 and individual taste sensitivity to glutamate. 31. annual meeting - Association for chemoreception sciences (AChemS)

[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionnucléotidegoûtglutamatehumangustation[SDV.AEN]Life Sciences [q-bio]/Food and Nutritionhomme
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Non synonymous nucleotide polymorphisms in human taste receptors and individual taste sensitivity to glutamate

2008

National audience

[SDV] Life Sciences [q-bio]GLUTAMATEHUMAN TASTE RECEPTORSINDIVIDUAL TASTE SENSITIVITY[SDV]Life Sciences [q-bio][INFO]Computer Science [cs][INFO] Computer Science [cs]ComputingMilieux_MISCELLANEOUSNUCLEOTIDE POLYMORPHISMS
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Relation phénotype-génotype dans le cas de la sensibilité gustative au glutamate

2009

National audience

[SDV] Life Sciences [q-bio]GLUTAMATESENSIBILITE GUSTATIVE[SPI.GPROC] Engineering Sciences [physics]/Chemical and Process Engineering[SDV]Life Sciences [q-bio][SDV.IDA]Life Sciences [q-bio]/Food engineering[INFO]Computer Science [cs][SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering[INFO] Computer Science [cs][SDV.IDA] Life Sciences [q-bio]/Food engineeringComputingMilieux_MISCELLANEOUS
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Phenotype genotype relationship in human taste

2008

International audience

[CHIM.OTHE] Chemical Sciences/Otherphenotypegenotypehuman taste[CHIM.OTHE]Chemical Sciences/OtherComputingMilieux_MISCELLANEOUS
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