0000000001137476

AUTHOR

Rodolfo Iuliano

showing 3 related works from this author

The receptor protein tyrosine phosphatase PTPRJ negatively modulates the CD98hc oncoprotein in lung cancer cells.

2018

PTPRJ, a receptor protein tyrosine phosphatase strongly downregulated in human cancer, displays tumor suppressor activity by negatively modulating several proteins involved in proliferating signals. Here, through a proteomic-based approach, we identified a list of potential PTPRJ-interacting proteins and among them we focused on CD98hc, a type II glycosylated integral membrane protein encoded by SLC3A2, corresponding to the heavy chain of a heterodimeric transmembrane amino-acid transporter, including LAT1. CD98hc is widely overexpressed in several types of cancers and contributes to the process of tumorigenesis by interfering with cell proliferation, adhesion, and migration. We first valid…

0301 basic medicineCD98hcChemistryCell growthCellPTPRJProtein tyrosine phosphatasemedicine.disease_causeProtein tyrosine phosphatase03 medical and health scienceschemistry.chemical_compound030104 developmental biologymedicine.anatomical_structureProteasomal degradationOncologyMG132Cancer cellCancer researchmedicineProteasome inhibitorGene silencingLung cancerCarcinogenesismedicine.drugResearch Paper
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Role of PTPRJ genotype in papillary thyroid carcinoma risk

2010

The strong genetic predisposition to papillary thyroid carcinoma (PTC) might be due to a combination of low-penetrance susceptibility variants. Thus, the research into gene variants involved in the increase of susceptibility to PTC is a relevant field of investigation. The gene coding for the receptor-type tyrosine phosphatase PTPRJ has been proposed as a cancer susceptibility gene, and its role as a tumor suppressor gene is well established in thyroid carcinogenesis. In this study, we want to ascertain the role of PTPRJ genotype in the risk for PTC. We performed a case–control study in which we determined the PTPRJ genotype for the non-synonymous Gln276Pro and Asp872Glu polymorphisms by PC…

RiskOncologyCancer Researchmedicine.medical_specialtyGenotypeendocrine system diseasesEndocrinology Diabetes and MetabolismBiologyPolymerase Chain ReactionArticleSettore MED/13 - EndocrinologiaThyroid carcinomaEndocrinologyGene FrequencyInternal medicineGenotypeOdds RatiomedicineGenetic predispositionHumansGenetic Predisposition to DiseaseThyroid NeoplasmsAlleleAllele frequencyAllelesGenetic Association StudiesPapillay thyroid carcinomaGeneticsChi-Square DistributionPolymorphism GeneticReceptor-Like Protein Tyrosine Phosphatases Class 3ThyroidCase-control studyCarcinoma PapillaryGenotype frequencymedicine.anatomical_structureOncologyCase-Control Studies
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¿Quién está buscando su mejor versión? Coaching y psicología deportiva en el proceso de terapeutización de (y desde) el golf

2020

This article asks about the expansion of psychological, therapeutic and self-enhancement ethos through the networks and devices that configures middle and upper-middle classes, and about the ways in which this process is singled out starting from the encounter between coaching and psychology paradigms with golf fans, in contemporary Argentina. The empirical materials that support the analysis have been ethnographically produced from the interaction with golf players and coaches.

self-enhancementPsicología DeportivaMejoramiento Personaland about the ways in which this process is singled out starting from the encounter between coaching and psychology paradigms with golf fansRodolfo This article asks about the expansion of psychological1137-7038 8537 Arxius de sociologia 562372 2020 42 7674034 ¿Quién está buscando su mejor versión? Coaching y psicología deportiva en el proceso de terapeutización de (y desde) el golf IulianoGolf.:SOCIOLOGÍA [UNESCO]Clases Mediassport psychologytherapeutic and self-enhancement ethos through the networks and devices that configures middle and upper-middle classescoachingUNESCO::SOCIOLOGÍAgolf 89 102in contemporary Argentina. The empirical materials that support the analysis have been ethnographically produced from the interaction with golf players and coaches. Coachingmiddle classes
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