Landscape reconstruction and major flood events of the River Main (Hesse, Germany) in the environs of the Roman fort at Groβkrotzenburg

Abstract Detailed geoarchaeological studies were conducted at the Groβkrotzenburg floodplain (Southern Hesse, Germany) in order to reconstruct the fluvial palaeogeography and search for Roman harbour installations. Another objective was to reconstruct the local flood history based on stratigraphic and geochronological data. Prospection based on electrical resistivity tomography, vibracoring and direct push electrical conductivity logging were carried out to detect and analyze subsurface stratigraphies. Altogether, 6 sediment cores, up to 7 m long, were drilled along transects along and perpendicular to the present course of the River Main. Based on sedimentological and geochemical data, we …

The impact of conversion on the risk of major complication following laparoscopic colonic surgery: an international, multicentre prospective audit.

BACKGROUND: Laparoscopy has now been implemented as a standard of care for elective colonic resection around the world. During the adoption period, studies showed that conversion may be detrimental to patients, with poorer outcomes than both laparoscopic completed or planned open surgery. The primary aim of this study was to determine whether laparoscopic conversion was associated with a higher major complication rate than planned open surgery in contemporary, international practice.METHODS: Combined analysis of the European Society of Coloproctology 2017 and 2015 audits. Patients were included if they underwent elective resection of a colonic segment from the caecum to the rectosigmoid jun…

Evaluating the incidence of pathological complete response in current international rectal cancer practice: the barriers to widespread safe deferral of surgery

INTRODUCTION: The mainstay of management for locally advanced rectal cancer is chemoradiotherapy followed by surgical resection. Following chemoradiotherapy, a complete response may be detected clinically and radiologically (cCR) prior to surgery or pathologically after surgery (pCR). We aim to report the overall complete pathological response (pCR) rate and the reliability of detecting a cCR by conventional pre-operative imaging.METHODS: A pre-planned analysis of the European Society of Coloproctology (ESCP) 2017 audit was performed. Patients treated by elective rectal resection were included. A pCR was defined as a ypT0 N0 EMVI negative primary tumour; a partial response represented any r…

Steppes of Southern Siberia - Experiences from the 6th EDGG Research Expedition to Khakassia, Russia (22 July – 1 August 2013)

The 6th EDGG Research Expedition took place in summer 2013 in the Kuznetsky Alatau Mountains, part of the Altai-Sayanian mountain region (Republic of Khakassia, Russia). A group of 14 scientists from seven countries studied the variety of steppe vegetation in two regions of the "Khakassky" Reserve – Lake Itkul (Shira region) and Podzaploty (Ordzhenikidzevsky region). Standardised sampling procedures including nested-plot series and phytosociological relevés of 10-m2 plots were used to sample steppes of European-Siberian (Festuco-Brometea) and Central Asian (Cleistogenetea squarrosae) types. All terricolous plants present in the plots were sampled, including perennial and annual vascular pla…

An international multicentre prospective audit of elective rectal cancer surgery; operative approach versus outcome, including transanal total mesorectal excision (TaTME)

Introduction: Transanal total mesorectal excision (TaTME) has rapidly emerged as a novel approach for rectal cancer surgery. Safety profiles are still emerging and more comparative data is urgently needed. This study aimed to compare indications and short-term outcomes of TaTME, open, laparoscopic, and robotic TME internationally. Methods: A pre-planned analysis of the European Society of Coloproctology (ESCP) 2017 audit was performed. Patients undergoing elective total mesorectal excision (TME) for malignancy between 1 January 2017 and 15 March 2017 by any operative approach were included. The primary outcome measure was anastomotic leak. Results: Of 2579 included patients, 76.2% (1966/257…

Impressions from the 4th EDGG Research Expedition to Sicily: community composition and diversity of Mediterranean grasslands.

Single cell transplantation reveals interspecific cell communication in Drosophila chimeras

Abstract Cell –cell communication is not only a common strategy for cell fate specification in vertebrates, but plays important roles in invertebrate development as well. We report here on experiments testing the compatibility of mechanisms specifying cell fate among six different Drosophila species. Following interspecific transplantation, the development of single ectodermal cells was traced in order to test their abilities to proliferate and differentiate in a heterologous environment. Despite considerable differences in cell size and length of cell cycle among some of the species, the transplants gave rise to fully differentiated clones that were integrated into the host tissue. Clones …