Solubility of solid carnosic acid in supercritical CO2 with ethanol as a co-solvent

Abstract The present study is devoted to the experimental measurement and thermodynamic modeling of solid carnosic acid solubility in supercritical CO 2  + ethanol as a co-solvent. Measurements were carried out at temperatures in the range of 313.15 and 333.15 K, pressures ranging from 280 to 400 bar, and at different content of the modifier ethanol (from 0.7 to 10%). The Group Contribution Associating Equation of State (GCA-EoS) [H.P. Gros, S.B. Bottini, E.A. Brignole, High pressure phase equilibrium modeling of mixtures containing associating compounds and gases, Fluid Phase Equilibria 139 (1997) 75–87] was applied in this work to represent the experimental solubility data obtained. Due t…