Ti6Al4V Surface Modification Techniques to Modulate Bone Cell Response: A Review

Biomaterial-tissue interactions are known to largely affect implant performance, relating to alteration of physiological processes. Within this context, metals continue to have a major role as most implants contain at least one metallic part. In particular, titanium alloys are of pivotal importance in orthopedics and dentistry. Being osteointegration somewhat affected by implant surface conditions, surface modifications, surface modification qualify as a way to modulate tissue response, net of an effective design of the whole implant. Currently, a lack of full understanding on the direction to be taken for proper techniques and process conditions to be employed, for the regulation of osteoi…