0000000001145419
AUTHOR
K. Wojcik
Risk for non-AIDS-defining and AIDS-defining cancer of early versus delayed initiation of antiretroviral therapy
BACKGROUND: Immediate initiation of antiretroviral therapy (ART) regardless of CD4 cell count reduces risk for AIDS and non-AIDS-related events in asymptomatic, HIV-positive persons and is the standard of care. However, most HIV-positive persons initiate ART when their CD4 count decreases below 500 × 10 9 cells/L. Consequences of delayed ART on risk for non-AIDS-defining and AIDS-defining cancer, one of the most common reasons for death in HIV, are unclear. OBJECTIVE: To estimate the long-term risk difference for cancer with the immediate ART strategy.DESIGN: Multinational prospective cohort study.SETTING: The D:A:D (Data collection on Adverse events of anti-HIV Drugs) study, which included…
Propagation non-linéaire d'impulsions femtosecondes dans une fibre optique à bande interdite à cœur solide
National audience; Nous décrivons une étude expérimentale et numérique de l'évolution non-linéaire d'impulsions ultrabrèves se propageant dans une fibre optique à bande interdite à coeur solide. Suivant le mécanisme de guidage employé, des dynamiques significativement différentes sont mises en évidence.