0000000001150033

AUTHOR

Valentina Bubba

showing 1 related works from this author

Serum alkaline phosphatase is elevated and inversely correlated with cognitive functions in subjective cognitive decline: results from the ReGAl 2.0 …

2020

Background: Alkaline phosphatase has been found on neuronal membranes and plasma alkaline phosphatase (ALP) activity increases during brain injury and cerebrovascular diseases, suggesting that its levels may reflect the neuronal loss. It is known that ALP is higher in subjects affected by Alzheimer’s dementia and inversely correlated with cognitive functions. No study has investigated the relationship between ALP and cognitive functions in old-age subject with pre-clinical cognitive impairment. Methods: This is a cross-sectional study with data gathered from the ReGAl 2.0 project (Rete Geriatrica Alzheimer-Geriatric Network on Alzheimer’s disease), a large Italian multicentric clinical-base…

medicine.medical_specialtyAgingGeriatric medicineAging Biochemistry Cognition Dementia Geriatric medicine Aged Alkaline Phosphatase Cognition Cross-Sectional Studies Humans Italy Neuropsychological Tests Alzheimer Disease Cognitive DysfunctionPopulationNeuropsychological TestsBiochemistry03 medical and health sciences0302 clinical medicineCognitionAlzheimer DiseaseInternal medicinemedicineMemory spanDementiaHumansCognitive Dysfunction030212 general & internal medicineCognitive declineeducationAgededucation.field_of_studybusiness.industryNeuropsychologyCognitionmedicine.diseaseAlkaline PhosphataseEndocrinologyCross-Sectional StudiesItalyCohortAlkaline phosphataseSettore MED/26 - NeurologiaDementiaGeriatrics and Gerontologybusiness030217 neurology & neurosurgery
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