0000000001160301

AUTHOR

E. Flynn

showing 4 related works from this author

Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

2019

Crohn Disease (CD) is a complex genetic disorder for which more than 140 genes have been identified using genome wide association studies (GWAS). However, the genetic architecture of the trait remains largely unknown. The recent development of machine learning (ML) approaches incited us to apply them to classify healthy and diseased people according to their genomic information. The Immunochip dataset containing 18,227 CD patients and 34,050 healthy controls enrolled and genotyped by the international Inflammatory Bowel Disease genetic consortium (IIBDGC) has been re-analyzed using a set of ML methods: penalized logistic regression (LR), gradient boosted trees (GBT) and artificial neural ne…

Male/692/4020/1503/257/1402GenotypeGenotyping TechniquesLOCI/45/43lcsh:MedicinePolymorphism Single NucleotideCrohn's disease genetics genome wide associationArticleDeep LearningCrohn DiseaseINDEL MutationGenetics researchHumansgeneticsGenetic Predisposition to Disease/129lcsh:ScienceAllelesScience & Technologygenome wide associationRISK PREDICTION/45Models Geneticlcsh:RDecision Trees/692/308/2056ASSOCIATIONMultidisciplinary SciencesCrohn's diseaseLogistic ModelsNonlinear DynamicsROC CurveArea Under CurveScience & Technology - Other Topicslcsh:QFemaleNeural Networks ComputerINFLAMMATORY-BOWEL-DISEASEGenome-Wide Association StudyScientific Reports
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Search for intermediate mass black hole binaries in the first and second observing runs of the Advanced LIGO and Virgo network

2019

Gravitational wave astronomy has been firmly established with the detection of gravitational waves from the merger of ten stellar mass binary black holes and a neutron star binary. This paper reports on the all-sky search for gravitational waves from intermediate mass black hole binaries in the first and second observing runs of the Advanced LIGO and Virgo network. The search uses three independent algorithms: two based on matched filtering of the data with waveform templates of gravitational wave signals from compact binaries, and a third, model-independent algorithm that employs no signal model for the incoming signal. No intermediate mass black hole binary event was detected in this sear…

binary: massneutron star: binaryAstronomybinary: angular momentumAstrophysicsdetector: network01 natural sciencesGeneral Relativity and Quantum CosmologyPhysics Particles & FieldsLIMITSclustersLIGOgravitational waveGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)QCQBastro-ph.HEPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)Settore FIS/01black hole: spinPhysicsintermediate mass black hole binarieNumerical relativityGeneral relativitygravitational wavesgravitational waves; intermediate mass black hole binaries; Advanced LIGO and VirgoPhysical Sciences[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc]Astrophysics - High Energy Astrophysical PhenomenastarsGeneral relativitygr-qcAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesalternative theories of gravitySTARS; CLUSTERS; LIMITSAstrophysics::Cosmology and Extragalactic AstrophysicsGeneral Relativity and Quantum Cosmology (gr-qc)Astronomy & Astrophysicsgravitational radiation: direct detectionGeneral Relativity and Quantum CosmologySettore FIS/05 - Astronomia e AstrofisicaBinary black hole0103 physical sciencesddc:530010306 general physicsAstrophysics::Galaxy AstrophysicsSTFCScience & Technology010308 nuclear & particles physicsGravitational waveAdvanced LIGO and Virgointermediate mass black hole binariesRCUKGravitational Wave Physicsblack hole: massMass ratiobinary: compact04.80.NnLIGOgravitational radiation detectorNeutron starVIRGOblack hole: binaryIntermediate-mass black holerelativity theorygravitational radiation: emission95.55.Ymmass ratioDewey Decimal Classification::500 | Naturwissenschaften::530 | Physik07.05.Kflimits[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]CLUSTERSSTARSGravitational waves Black holes (astronomy) Gravitational self force
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Search for Gravitational-wave Signals Associated with Gamma-Ray Bursts during the Second Observing Run of Advanced LIGO and Advanced Virgo

2019

We present the results of targeted searches for gravitational-wave transients associated with gamma-ray bursts during the second observing run of Advanced LIGO and Advanced Virgo, which took place from 2016 November to 2017 August. We have analyzed 98 gamma-ray bursts using an unmodeled search method that searches for generic transient gravitational waves and 42 with a modeled search method that targets compact-binary mergers as progenitors of short gamma-ray bursts. Both methods clearly detect the previously reported binary merger signal GW170817, with p-values of <9.38 10-6 (modeled) and 3.1 10-4 (unmodeled). We do not find any significant evidence for gravitational-wave signals associate…

Burst astrophysicAstrofísicaneutron star: binary010504 meteorology & atmospheric sciencesBinary numberAstrophysics01 natural sciencesLIGOQCSUPERNOVArelativistic jetsQBHigh Energy Astrophysical Phenomena (astro-ph.HE)Settore FIS/01counterpartGRBGravitational waves (678)Physical SciencesRELATIVISTIC JETSAstrophysics - High Energy Astrophysical PhenomenaGravitational waveGravitationstarsblack-holeAstrophysics::High Energy Astrophysical PhenomenaGeneral Relativity and Quantum Cosmology (gr-qc)precursor activityGravitational wavesSettore FIS/05 - Astronomia e AstrofisicasupernovaCORE-COLLAPSEGamma-ray burstGravitational wave sourcesScience & TechnologyVirgoRCUKAstronomy and AstrophysicsHigh energy astrophysics (739)RedshiftDewey Decimal Classification::500 | Naturwissenschaften::520 | Astronomie Kartographiedetector: sensitivityVIRGOSpace and Planetary Sciencegravitational radiation: emissionBLACK-HOLEddc:520Gravitational wave astronomyGamma-ray burst[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]STARSGravitacióAstronomySignalGeneral Relativity and Quantum CosmologyBurst astrophysicslocalizationemission010303 astronomy & astrophysicsPhysicsDetectorGamma-ray bursts (629)[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc]Gravitational wave sourcePRECURSOR ACTIVITYGamma-ray burstsLIGO (920)High energy astrophysicsdata analysis methodBurst astrophysics (187)FOS: Physical sciencesAstrophysics::Cosmology and Extragalactic Astrophysicsgamma ray: burstAstronomy & AstrophysicsMASSgravitational radiation: direct detectionGravitational wave astronomy Gravitational wave sources LIGO; Gravitational waves Gamma-ray bursts Burst astrophysics High energy astrophysicsGravitational wave astronomy (675)electromagnetic field: production0103 physical sciencesnumerical calculationsGRB; gravitational waves; LIGO; VirgoSTFC0105 earth and related environmental sciencesgravitational wavesneutron starsGravitational waveCOUNTERPARTgravitational radiationLIGOcore-collapsegravitational radiation detectorGravitational wave sources (677)radiationNeutron starPhysics and AstronomymassRADIATIONEMISSIONGravitational wave astronomy; Gravitational wave sources; LIGO; Gravitational waves; Gamma-ray bursts; Burst astrophysics; High energy astrophysics
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Search for GW signals associated with GRBs

2021

We present the results of targeted searches for gravitational-wave transients associated with gamma-ray bursts during the second observing run of Advanced LIGO and Advanced Virgo, which took place from 2016 November to 2017 August. We have analyzed 98 gamma-ray bursts using an unmodeled search method that searches for generic transient gravitational waves and 42 with a modeled search method that targets compact-binary mergers as progenitors of short gamma-ray bursts. Both methods clearly detect the previously reported binary merger signal GW170817, with p-values of <9.38x10^-6^ (modeled) and 3.1x10^-4^ (unmodeled). We do not find any significant evidence for gravitational-wave signals assoc…

Astrophysics and AstronomyGamma-ray astronomyhigh energy astrophysicsAstrophysics::High Energy Astrophysical PhenomenaPhysicsAstrophysics::Cosmology and Extragalactic Astrophysicsstellar astronomyGamma ray burstsGravitational wavesCosmologyobservational astronomyGamma ray astronomyGamma-ray burstsAstrophysical ProcessesNatural Sciences
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