0000000001166017

AUTHOR

Arsalan Augend

showing 1 related works from this author

Analysis of methylation and mRNA expression status ofFADD andFAS genes in patients with oral squamous cell carcinoma

2014

Background: Apoptosis is an important mechanism that is responsible for the physiological deletion of harmful, damaged, or unwanted cells. Changed expression of apoptosis-related genes may lead to abnormal cell proliferation and finally to tumorigenesis. Our aims were to analyze the promoter methylation and gene expression profiles of FADD and FAS genes in risk of OSCC. Material and Methods: we analyze the promoter methylation status of FADD and FAS genes using Methylation - Specific PCR (MSP) in 86 OSCC tissues were kept in paraffin and 68 normal oral tissues applied as control. Also, FADD and FAS genes expression were analyzed in 19 cases and 20 normal specimens by Real-Time Reverse- Tran…

MaleMrna expressionFas-Associated Death Domain ProteinOdontologíamedicine.disease_causeurologic and male genital diseasesGene expressionmedicineHumansIn patientFADDRNA Messengerfas ReceptorGeneral DentistryGeneOral Medicine and PathologybiologyResearchMethylationDNA MethylationMiddle Aged:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludOtorhinolaryngologyApoptosisUNESCO::CIENCIAS MÉDICASbiology.proteinCancer researchCarcinoma Squamous CellSurgeryFemaleMouth Neoplasmsbiological phenomena cell phenomena and immunityCarcinogenesisMedicina Oral, Patología Oral y Cirugía Bucal
researchProduct