0000000001178461
AUTHOR
A. Lo Presti
Successo occupazionale e nuove forme di organizzazione del lavoro
Quali sono le risorse fondamentali che decidono del successo e della fortuna di ogni organizzazione? Senza dubbio le persone. Per questo i processi di gestione e sviluppo delle persone meritano particolare attenzione e richiedono investimenti significativi capaci di garantire efficacia organizzativa e qualità della vita di lavoro. La psicologia delle risorse umane rappresenta un ambito disciplinare articolato, che si propone di rispondere a tutti gli interrogativi concernenti la relazione tra persone e organizzazioni dal punto di vista della realizzazione di condizioni di reciproca soddisfazione. Obiettivo del manuale è affrontare in sedici capitoli le principali questioni in gioco in tale …
Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes
Background Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage ≥3 CKD has been less explored in type 1 diabetes mellitus (T1DM) patients. Aim of the present study was to evaluate the prognostic role of kidney disease measures, namely albuminuria and reduced GFR, on the development of stage ≥3 CKD in a large cohort of patients affected by T1DM. Methods A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici D…
Holoprosencephaly: examples of clinical variability and etiologic heterogeneity.
Clinical variability and causal heterogeneity of holoprosencephaly is discussed in relation to several newborn infants with cyclopia (cases 4,5,6), cebocephaly (cases 2,3), and premaxillary agenesis (case 1). In subjects with holoprosencephaly, the presence of multiple malformations is an indicator of concomitant chromosome aberrations, as in present case 1 (Down syndrome) and case 3 (trisomy 13). Cases 5 and 6 are two monozygotic twins with the same type of cyclopia and alobar holoprosencephaly recognized by prenatal ultrasonography. The diagnostic importance of ultrasonographic, cytogenetic, and pathological studies is pointed out in view of etiologic evaluation, genetic counseling, and p…
Co-circulation of SARS-CoV-2 Alpha and Gamma variants in Italy, February and March 2021
Background Several SARS-CoV-2 variants of concern (VOC) have emerged through 2020 and 2021. There is need for tools to estimate the relative transmissibility of emerging variants of SARS-CoV-2 with respect to circulating strains. Aim We aimed to assess the prevalence of co-circulating VOC in Italy and estimate their relative transmissibility. Methods We conducted two genomic surveillance surveys on 18 February and 18 March 2021 across the whole Italian territory covering 3,243 clinical samples and developed a mathematical model that describes the dynamics of co-circulating strains. Results The Alpha variant was already dominant on 18 February in a majority of regions/autonomous provinces (…