0000000001183986

AUTHOR

J Smith

showing 9 related works from this author

Elective Cancer Surgery in COVID-19-Free Surgical Pathways during the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study

2020

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a …

MaleCancer ResearchOutcome AssessmentInternational CooperationSettore MED/18 - CHIRURGIA GENERALESettore MED/19 - Chirurgia Plastica030230 surgeryAged; Aged 80 and over; COVID-19; Cohort Studies; Critical Care; Elective Surgical Procedures; Epidemics; Female; Humans; International Cooperation; Logistic Models; Male; Middle Aged; Neoplasms; Outcome Assessment Health Care; Postoperative Complications; SARS-CoV-2Cohort Studies0302 clinical medicineOperating theaterPostoperative Complicationscohort studiesNeoplasmsHealth caremiddle agedOutcome Assessment Health Care80 and overMedicineLungCancerCOVID-19/epidemiologyAged 80 and overOUTCOMESManchester Cancer Research CentrePulmonary ComplicationORIGINAL REPORTSMiddle AgedagedOncologyElective Surgical Procedures030220 oncology & carcinogenesisPneumonia & InfluenzaFemalePatient SafetyElective Surgical ProcedureLife Sciences & Biomedicine6.4 SurgeryCohort studyHumanmedicine.medical_specialtyelective surgical procedures/methodsLogistic ModelCritical CareAged; Aged; 80 and over; COVID-19; Cohort Studies; Critical Care; Elective Surgical Procedures; Epidemics; Female; Humans; International Cooperation; Logistic Models; Male; Middle Aged; Neoplasms; Outcome Assessment; Health Care; Postoperative Complications; SARS-CoV-2Clinical SciencesOncology and CarcinogenesisEpidemic[SDV.CAN]Life Sciences [q-bio]/Cancer-.cancer surgery ; COVID-19 ; SARS-CoV-2 pandemicepidemicsCOVIDSurg CollaborativeNOoutcome assessment health care/methods03 medical and health sciencesmaleSettore MED/28 - Malattie OdontostomatologicheClinical ResearchHumans1112 Oncology and CarcinogenesisOncology & CarcinogenesisElective surgeryEpidemicsElective Cancer Surgery in SARS-CoV-2 Elective Cancer Surgery in COVID-19 covid 19 sars-cov-2AgedScience & TechnologyElective Surgical Procedurebusiness.industrySARS-CoV-2PreventionResearchInstitutes_Networks_Beacons/mcrcEvaluation of treatments and therapeutic interventionsCOVID-191103 Clinical SciencesPneumoniaOdds ratiomedicine.diseaseHealth CarePneumoniaGood Health and Well Beingneoplasms/surgeryLogistic Modelscritical care/methodsEmergency medicinepostoperative complications/prevention & controlNeoplasmPostoperative ComplicationCohort Studiebusinessaged 80 and overSARS-CoV-2/physiologylogistic models
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Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic

2021

Association of Surgeons in Training Surgical Summit, online, 17 Oct 2020 - 17 Oct 2020 2021 Virtual Annual Meeting / Surgical Research Society, online, 24 Mar 2021 - 25 Mar 2021, National Research Collaborative Meeting, online, 10 Dec 2020 - 10 Dec 2020, Royal Australasian College of Surgeons Annual Academic Surgery Conference, online, 5 Nov 2020 - 5 Nov 2020; The British journal of surgery : BJS 108(12), 1448-1464 (2021). doi:10.1093/bjs/znab336

MaleRespiration Artificial/statistics & numerical dataSettore MED/18 - CHIRURGIA GENERALEeducation-Sciences du Vivant [q-bio]/Médecine humaine et pathologieAbdominal NeoplasmPostoperative Complications/mortalityNOsurgeryCohort Studies03 medical and health sciencesCOVID-19; death; SARS-CoV-2; surgery0302 clinical medicinePostoperative ComplicationsdeathHumans030212 general & internal medicinePandemicsAbdominal Neoplasms/surgeryAgedLS7_4COVID-19/mortalityRespiratory Distress SyndromePandemicSARS-CoV-2Respirationsurgical procedures operativemortalitysurgery specialtypandemicspulmonary complicationssars-cov-2covid-19coronavirus pandemicCOVID-19Middle Aged3126 Surgery anesthesiology intensive care radiologyRespiration Artificialsurgical proceduresoperativemortalitysurgery specialtypandemicspulmonary complicationssars-cov-2covid-19coronavirus pandemicAbdominal Neoplasms; Aged; COVID-19; Cohort Studies; Female; Humans; Male; Middle Aged; Pandemics; Postoperative Complications; Respiration Artificial; Respiratory Distress Syndrome; Elective Surgical ProceduresElective Surgical Procedures030220 oncology & carcinogenesisAbdominal NeoplasmsArtificialFemalePostoperative ComplicationCohort Studie[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyRespiratory Distress Syndrome/mortalityHuman
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Delaying surgery for patients with a previous SARS-CoV-2 infection

2020

With at least 28 elective million operations delayed during the first three months of the COVID-19 pandemic, the number of patients who will require surgery after a previous SARS-CoV-2 infection is likely to increase rapidly1. Operating on patients with an active perioperative SARS-CoV-2 infection is now known to carry a very high pulmonary complication and mortality rate2. Urgent information is needed to guide whether postponing surgery in patients with a previous SARS-CoV-2 infection leads to a clinical benefit, and the optimal length of delay.

SARS Virus Coronavirus Severe Acute Respiratory Syndrome cancersurgery pandemic infectionSettore MED/06 - Oncologia MedicaSettore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALECOVID-19. Global surgery.Settore MED/19 - Chirurgia PlasticaComorbidity030230 surgeryCovidCOVID-19 / epidemiologysurgery0302 clinical medicineNeoplasms / surgeryNeoplasmsCOVID-19; Comorbidity; Humans; Neoplasms; Surgical Procedures Operative; Pandemics; SARS-CoV-2; Time-to-TreatmentProspective cohort study610 Medicine & healthCOVID-19/epidemiologymedicine.diagnostic_testSurgery sars-cov-2 covid surg surgery pandemic infectionPulmonary ComplicationSARS cov 2Covid19Surgical Procedures Operative / methodsOperativesurgery; Sars-CoV-2Surgical Procedures OperativeSurgery sars-cov-2Neoplasms / epidemiologyCohort studyHumanmedicine.medical_specialtySciences du Vivant [q-bio]/Médecine humaine et pathologieNOTime-to-TreatmentThroat culture03 medical and health sciencesSettore MED/28 - Malattie OdontostomatologichemedicineResearch LetterHumansElective surgeryGeneralPandemicscovid surgSurgical ProceduresPandemicbusiness.industrySARS-CoV-2No key words availablePostoperative complicationCOVID-19Perioperativemedicine.diseaseSurgeryPneumoniaSettore MED/40 - GINECOLOGIA E OSTETRICIANeoplasmSurgical Procedures Operative/methodsSurgerybusinessNeoplasms/epidemiology[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Search for CP violation in D (+/-) -> (KSK +/-)-K-0 and D-s(+/-) -> K-S(0)pi(+/-) decays

2014

A search for \CP violation in Cabibbo-suppressed $D^{\pm}\rightarrow K^0_{\mathrm{S}} K^{\pm}$ and $D^{\pm}_{s}\rightarrow K^0_{\mathrm{S}} \pi^{\pm}$ decays is performed using $pp$ collision data, corresponding to an integrated luminosity of 3~fb$^{-1}$, recorded by the LHCb experiment. The individual $CP$-violating asymmetries are measured to be \begin{eqnarray*} \mathcal{A}_{CP}^{D^{\pm}\rightarrow K^0_{\mathrm{S}} K^{\pm}} & = & (+0.03 \pm 0.17 \pm 0.14) \% \mathcal{A}_{CP}^{D^{\pm}_{s}\rightarrow K^0_{\mathrm{S}} \pi^{\pm}} & = & (+0.38 \pm 0.46 \pm 0.17) \%, \end{eqnarray*} assuming that $CP$ violation in the Cabibbo-favoured decays is negligible. A combination of the measured asymmet…

Nuclear and High Energy PhysicsParticle physicsSDG 16 - Peacemedia_common.quotation_subjectCP violation; Hadron-Hadron ScatteringDalitz plotLHCb - Abteilung HofmannHadrons01 natural sciencesAsymmetryNOSettore FIS/04 - Fisica Nucleare e SubnucleareNuclear physicsTEV PP COLLISIONS; PRODUCTION ASYMMETRY0103 physical sciencesCP violation hadron-hadron scatteringPiTEV PP COLLISIONS010306 general physicsLarge Hadron Collider (France and Switzerland)PRODUCTION ASYMMETRYQCmedia_commonPhysicsLuminosity (scattering theory)Hadron-Hadron Scattering010308 nuclear & particles physicshep-exSDG 16 - Peace Justice and Strong InstitutionsHigh Energy Physics::PhenomenologyGran Col·lisionador d'HadronsParticle physicsPhi meson/dk/atira/pure/sustainabledevelopmentgoals/peace_justice_and_strong_institutionsJustice and Strong InstitutionsCP violationCP violationHigh Energy Physics::ExperimentFísica nuclearFísica de partículesExperimentsParticle Physics - Experiment
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Measurement of polarization amplitudes and CP asymmetries in B 0 → Φk *(892)0

2014

An angular analysis of the decay $B^0 \to \phi K^*(892)^0$ is reported based on a $pp$ collision data sample, corresponding to an integrated luminosity of 1.0 fb$^{-1}$, collected at a centre-of-mass energy of $\sqrt{s} = 7$ TeV with the LHCb detector. The P-wave amplitudes and phases are measured with a greater precision than by previous experiments, and confirm about equal amounts of longitudinal and transverse polarization. The S-wave $K^+ \pi^-$ and $K^+K^-$ contributions are taken into account and found to be significant. A comparison of the $B^0 \to \phi K^*(892)^0$ and $\bar{B}^0 \to \phi \bar{K}^*(892)^0$ results shows no evidence for direct CP violation in the rate asymmetry, in th…

B physic12.15.MmB physicsLuminosityHigh Energy Physics - ExperimentSettore FIS/04 - Fisica Nucleare e SubnucleareNeutral current13.88.+ePolarization[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]TOOLmedia_commonPhysicsPhysicsPHYSICS PARTICLES & FIELDSParticle physicsCharge conjugation parity time reversal and other discrete symmetriePolarization (waves)Transverse planeAmplitudeCP violationPhysical SciencesCP violationFísica nuclearLHCParticle Physics - ExperimentParticle physicsNuclear and High Energy Physicsmedia_common.quotation_subject14.40.NdFlavour Changing Neutral CurrentsLHCb - Abteilung HofmannHadronsAsymmetryDECAYSHadronic decays of bottom mesonDISTRIBUTIONSLarge Hadron Collider (France and Switzerland)B physics; CP violation; Flavour Changing Neutral Currents; Hadron-Hadron Scattering; Polarization; Nuclear and High Energy PhysicsScience & TechnologyFlavour Changing Neutral CurrentHadron-Hadron ScatteringB physics; CP violation; Flavour Changing Neutral Currents; Hadron-Hadron Scattering; PolarizationGran Col·lisionador d'HadronsLHCb13.25.HwBottom mesons (|B|>0)11.30.ErHigh Energy Physics::ExperimentFísica de partículesExperimentsPolarization in interactions and scatteringEnergy (signal processing)Bar (unit)
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Genome sequence of the pea aphid Acyrthosiphon pisum

2010

The genome of the pea aphid shows remarkable levels of gene duplication and equally remarkable gene absences that shed light on aspects of aphid biology, most especially its symbiosis with Buchnera.

0106 biological sciencesTANDEM REPEATSGenome InsectGene TransferRRES175Sequència genòmicaFaculty of Science\Computer ScienceCPG METHYLATION01 natural sciencesGenomeMedical and Health SciencesInternational Aphid Genomics ConsortiumBiologiska vetenskaperBiology (General)GENE-EXPRESSION2. Zero hungerGenetics0303 health sciencesAphidGenomeAfídidsGeneral NeuroscienceGENOME SEQUENCEfood and beveragesDROSOPHILA CIRCADIAN CLOCKBiological SciencesGenetics and Genomics/Microbial Evolution and GenomicsINSECTEGenètica microbianapuceronAPIS-MELLIFERAGeneral Agricultural and Biological SciencesInfectionsymbioseBiotechnologyResearch ArticleVIRUS VECTORING175_GeneticsSYMBIOTIC BACTERIAGene Transfer HorizontalQH301-705.5ACYRTHOSIPHON PISUMBiologyHOLOMETABOLOUS INSECTSHOST-PLANT010603 evolutionary biologyGENOME SEQUENCE;PEA APHID;ACYRTHOSIPHON PISUM;INSECT-PLANT;HOST-PLANT;VIRUS VECTORING;PHENOTYPIC PLASTICITY;HOLOMETABOLOUS INSECTS;INSECTE;RAVAGEUR DES CULTURES; SOCIAL INSECTGeneral Biochemistry Genetics and Molecular BiologyHorizontal03 medical and health sciencesBuchneraPHENOTYPIC PLASTICITYINSECT-PLANTGeneticsGene familyLife ScienceAnimalsSymbiosisGene030304 developmental biologyWhole genome sequencingGeneral Immunology and MicrobiologyAnnotation; Aphid; Genome sequenceAgricultural and Veterinary Sciences175_EntomologyGenètica animalBacteriocytegénomegèneHuman GenomePEA APHIDBiology and Life Sciences15. Life on landbiochemical phenomena metabolism and nutritionbiology.organism_classificationREPETITIVE ELEMENTSDNA-SEQUENCESAcyrthosiphon pisumGenome SequenceGenetics and Genomics/Genome ProjectsRAVAGEUR DES CULTURESAphidsPHEROMONE-BINDINGBuchneraInsectDevelopmental Biology[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study

2021

This international, prospective, cohort study enrolled 20 006 adult (≥18 years) patients from 466 hospitals in 61 countries with 15 cancer types, who had a decision for curative surgery during the COVID-19 pandemic and were followed up until the point of surgery or cessation of follow-up (Aug 31, 2020). Average national Oxford COVID-19 Stringency Index scores were calculated to define the government response to COVID-19 for each patient for the period they awaited surgery, and classified into light restrictions (index 60). The primary outcome was the non-operation rate (defined as the proportion of patients who did not undergo planned surgery). Cox proportional-hazards regression models wer…

MaleCOVID-19 COVIDSURG COVIDSURG CANCEROutcome AssessmentIMPACTSettore MED/18 - CHIRURGIA GENERALEBIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Surgery.surgeryCancer surgeryNeoplasms/classificationBIOMEDICINA I ZDRAVSTVO. Javno zdravstvo i zdravstvena zaštita.Surgical oncologyNeoplasmsAcute careCOVID-19 - epidemiologyOutcome Assessment Health CareMedicine and Health Sciences80 and overGlobal healthtimingProspective StudiesUK610 Medicine & healthProspective cohort studyCOVID-19/epidemiologyCOVIDAged 80 and overBIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Oncology.BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Kirurgija.Hazard ratioArticlesMiddle AgedOncologyAdult; Aged; Aged 80 and over; Communicable Disease Control; COVID-19; Female; Humans; Male; Middle Aged; Neoplasms; Outcome Assessment Health Care; Proportional Hazards Models; Prospective Studies; SARS-CoV-2; Time-to-Treatment; Withholding Treatment/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemalecancer surgeryCovid-19Life Sciences & BiomedicineMENTAL-HEALTHmental healthCohort studyHumanAdultmedicine.medical_specialtydelay3122 CancersCOVID-19 - prevention and control610 Medicine & healthCOVIDSurg CollaborativeNOTime-to-TreatmentSDG 3 - Good Health and Well-beingLockdownmedicineHumanscancer1112 Oncology and CarcinogenesisOncology & CarcinogenesisElective surgeryLS7_4Proportional Hazards ModelsAgedScience & Technologybusiness.industrySARS-CoV-2Public healthGeneral surgeryBIOMEDICINE AND HEALTHCARE. Public Health and Health Care.COVID-193126 Surgery anesthesiology intensive care radiologyHealth CareCommunicable Disease Control/legislation & jurisprudenceProspective StudieWithholding TreatmentCOVID-19; delay; SARS-CoV-2; surgery; timing; cancer surgery;COVID-19 ; lockdowns ; cancer surgeryCommunicable Disease ControlBIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Onkologija.Proportional Hazards ModelNeoplasmbusiness
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Angular analysis of charged and neutral B → Kμ + μ − decays

2014

The angular distributions of the rare decays B → K+µ+µ- and B0 → K0 <inf>a</inf>Sμ+μ- are studied with data corresponding to 3 fb-1 of integrated luminosity, collected in proton-proton collisions at 7 and 8TeV centre-of-mass energies with the LHCb detector. The angular distribution is described by two parameters, FH and the forward-backward asymmetry of the dimuon system AFB, which are determined in bins of the dimuon mass squared. The parameter F<inf>H</inf> is a measure of the contribution from (pseudo)scalar and tensor amplitudes to the decay width. The measurements of A<inf>FB</inf> and F<inf>H</inf> reported here are the most precise to d…

B physic12.15.MmB physicsSettore FIS/04 - Fisica Nucleare e SubnucleareLuminosityNeutral currentFlavor physicsMathematics::ProbabilityNuclear Experimentmedia_commonPhysicsB physics; Flavor physics; Flavour changing neutral currents; Hadron-hadron scattering; Rare decayPhysicsPHYSICS PARTICLES & FIELDSParticle physicsAmplitudePhysical SciencesFísica nuclearLHCNuclear and High Energy PhysicsParticle physicsmedia_common.quotation_subject14.40.NdScalar (mathematics)Flavour Changing Neutral CurrentsMathematics::Analysis of PDEsLHCb - Abteilung HofmannHadronsMeasure (mathematics)AsymmetryMathematics::Numerical AnalysisStandard ModelAngular distributionTheoryofComputation_ANALYSISOFALGORITHMSANDPROBLEMCOMPLEXITYLeptonic semileptonic and radiative decays of bottom mesonSDG 7 - Affordable and Clean EnergyTensorLarge Hadron Collider (France and Switzerland)Science & Technology/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energyHadron-Hadron ScatteringGran Col·lisionador d'HadronsFlavour changing neutral currentLHCbRare decay13.20.HeFlavor physicBottom mesons (|B|>0)High Energy Physics::ExperimentFísica de partículesExperiments
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Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pand…

2021

Abstract Background Surgical services are preparing to scale up in areas affected by COVID-19. This study aimed to evaluate the association between preoperative SARS-CoV-2 testing and postoperative pulmonary complications in patients undergoing elective cancer surgery. Methods This international cohort study included adult patients undergoing elective surgery for cancer in areas affected by SARS-CoV-2 up to 19 April 2020. Patients suspected of SARS-CoV-2 infection before operation were excluded. The primary outcome measure was postoperative pulmonary complications at 30 days after surgery. Preoperative testing strategies were adjusted for confounding using mixed-effects models. Results Of 8…

Lung DiseasesMalexAcademicSubjects/MED00910COVID-19/diagnosisSettore MED/18 - CHIRURGIA GENERALEneoplasms030230 surgeryminorsurgical proceduresMedical and Health SciencesLung Disease0302 clinical medicinePostoperative Complications030202 anesthesiologyaged; aged 80 and over; COVID-19; elective surgical procedures; female; humans; lung diseases; male; middle aged; Nasopharynx; neoplasms; pandemics; postoperative complications; risk assessment; SARS-CoV-2; COVID-19 nucleic acid testingNeoplasmsNasopharynx80 and over030212 general & internal medicine610 Medicine & healthLungCancerlung diseasesAged 80 and overIncidence (epidemiology)ConfoundingPulmonary ComplicationLung Diseases/*etiologyNeoplasms/surgeryGeneral MedicineMiddle AgedElective Surgical Procedures/adverse effectsOncologyElective Surgical Procedures030220 oncology & carcinogenesisCOVID-19 Nucleic Acid TestingOriginal ArticleFemalePatient SafetyAcademicSubjects/MED00010Elective Surgical Procedure6.4 SurgeryHumanCohort studymedicine.medical_specialtypreoperative caresurgical proceduresCOVID-19 nucleic acid testing.elective surgical proceduresPreoperative careRisk AssessmentArticleCOVIDSurg CollaborativeNO*COVID-19 Nucleic Acid TestingVaccine Related03 medical and health sciencesClinical ResearchBiodefensemedicineNasopharynx/*virologyHumansNasopharynx/virologyElective surgeryAdverse effectPandemicsLS7_4AgedElective Surgical ProcedurePandemicbusiness.industrySARS-CoV-2Surgery Sars Cov2PreventionNo key words availableelectivesurgical proceduresLung Diseases/etiologyEvaluation of treatments and therapeutic interventionsCancerPostoperative complicationoperativenasopharynxsurgery specialtypulmonary complicationscancer surgerysars-cov-2covid-19coronavirus pandemicCOVID-19Odds ratiomedicine.diseaseConfidence intervalSurgeryCOVID-19/*diagnosisEmerging Infectious DiseasesGood Health and Well BeingNeoplasmSurgeryPostoperative Complicationpreoperative caresurgical procedures electivesurgical procedures minorsurgical procedures operativenasopharynxsurgery specialtypulmonary complicationscancer surgerysars-cov-2covid-19coronavirus pandemicElective Surgical Procedures/*adverse effectsbusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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