0000000001184328

AUTHOR

F. Melandro

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Machine Perfusions in Liver Transplantation: The Evidence‐Based Position Paper of the Italian Society of Organ and Tissue Transplantation

2020

The use of machine perfusion (MP) in liver transplantation (LT) is spreading worldwide. However, its efficacy has not been demonstrated, and its proper clinical use has far to go to be widely implemented. The Società Italiana Trapianti d’Organo (SITO) promoted the development of an evidence-based position paper. A 3-step approach has been adopted to develop this position paper. First, SITO appointed a chair and a cochair who then assembled a working group with specific experience of MP in LT. The Guideline Development Group framed the clinical questions into a patient, intervention, control, and outcome (PICO) format, extracted and analyzed the available literature, ranked the quality of th…

medicine.medical_specialtyEvidence-based practice2747 TransplantationGRADE; donor after circulatory death; donor brain death; hypothermic machine; liver transplant; machine perfusion; normothermic machine; normothermic regional perfusion; position papermedicine.medical_treatmentDelphi methodMEDLINEhypothermic machine610 Medicine & healthdonor after circulatory deathliver perfusion machine030230 surgeryLiver transplantationnormothermic regional perfusionliver03 medical and health sciences0302 clinical medicinenormothermic machineHumansMedicineMedical physics10217 Clinic for Visceral and Transplantation SurgeryHumansItalyTransplantationMachine perfusionHepatologybusiness.industrymachine perfusionOrgan Preservationdonor brain deathperfusion machineInstitutional review boardLiver Transplantation2746 SurgeryPerfusionTransplantationliver transplantGRADEItalyPosition paper2721 Hepatology030211 gastroenterology & hepatologySurgerybusinessposition paperHumanLiver Transplantation
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