0000000001192832
AUTHOR
Pierre Boureau
Maternal Western Diet” feeding of rat dams leads to profound plasticity and GABAergic phenotype changes within reward pathway from birth to sexual maturity in the offspring
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Perinatal Western Diet Consumption Leads to Profound Plasticity and GABAergic Phenotype Changes within Hypothalamus and Reward Pathway from Birth to Sexual Maturity in Rat
This article is part of the Research Topic Early Life Origins of Obesity and Type 2 Diabetes.; International audience; Perinatal maternal consumption of energy dense food increases the risk of obesity in children. This is associated with an overconsumption of palatable food that is consumed for its hedonic property. The underlying mechanism that links perinatal maternal diet and offspring preference for fat is still poorly understood. In this study, we aim at studying the influence of maternal high-fat/high-sugar diet feeding [western diet (WD)] during gestation and lactation on the reward pathways controlling feeding in the rat offspring from birth to sexual maturity. We performed a longit…
Impact of perinatal over-nutrition on the developing sweet/fatty taste and the ontogeny of brain reward pathway, from birth to sexual maturity in rat
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Perinatal Western Diet consumption leads to a profound change in plasticity and GABAergic phenotype within hypothalamus and reward pathway from birth to sexual maturity in rat
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Impact of an unbalanced diet on the acquisition of food preferences and the development of reward circuits in rat
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Consuming a balanced diet from weaning reverses the programming of food preferences in offspring of Western-Diet-fed rat dams
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