0000000001203287
AUTHOR
Giovanni Guarneri
showing 5 related works from this author
Psicoprofilassi ostetrica e depressione puerperale
2004
Adolescenti ed uso delle nuove tecnologie. Una ricerca esplorativa
2008
ADOLESCENTI E USO DELLE NUOVE TECNOLOGIE - UNA RICERCA ESPLORATIVA.
2008
Infezione da HIV nel tratto genitale femminile. Diffusione virale ed immunità locale
2007
What are the Cancer Risks in BRCA Carriers Apart from Those Regarding the Breast and the Ovary?
2012
Germline mutations in the tumor suppressor genes BRCA1 and BRCA2 predispose to familial breast and/or ovarian cancer. The lifetime risk of members of families with genetic predisposition depends on the mutations of susceptibility genes. BRCA1 mutations seem to confer the highest risk of developing neoplastic diseases. Apart from breast and ovarian cancer mutations in BRCA, related pathways are supposed to confer a smaller risk for additional cancers (colon, melanoma, pancreas, lymphoma, prostate, liver). All these tumors have an inherited component not necessarily associated with genetic susceptibility to BRCA genes. To date he main focus of this review has been argued still with difficulty…