0000000001208539

AUTHOR

Gupta

showing 5 related works from this author

Association of mechanical bowel preparation with oral antibiotics and anastomotic leak following left sided colorectal resection: an international, m…

2018

INTRODUCTION: The optimal bowel preparation strategy to minimise the risk of anastomotic leak is yet to be determined. This study aimed to determine whether oral antibiotics combined with mechanical bowel preparation (MBP+Abx) was associated with a reduced risk of anastomotic leak when compared to mechanical bowel preparation alone (MBP) or no bowel preparation (NBP).METHODS: A pre-planned analysis of the European Society of Coloproctology (ESCP) 2017 Left Sided Colorectal Resection audit was performed. Patients undergoing elective left sided colonic or rectal resection with primary anastomosis between 1 January 2017 and 15 March 2017 by any operative approach were included. The primary out…

Laparoscopic surgeryMaleLeakmedicine.medical_specialtyCathartics/administration & dosagemedicine.drug_classmedicine.medical_treatmentAntibioticsanastomotic leakanastomotic leak; bowel preparation; colonic cancer; Colorectal surgery; laparoscopic surgery; Gastroenterology030230 surgeryAnastomosisPreoperative Care/methodsNO03 medical and health sciences0302 clinical medicineColorectal surgeryAnti-Bacterial Agents/administration & dosagePreoperative CareMedicineHumansrisk factorsProspective StudiesMulti centreProspective cohort studyColectomyAgedta3126Medical Auditbusiness.industryCatharticsdigestive oral and skin physiologyGastroenterologycolonic cancerMiddle Agedlaparoscopic surgeryColorectal surgerydigestive system diseasesSurgeryAnti-Bacterial Agents030220 oncology & carcinogenesisBowel preparationbowel preparationDrug Therapy CombinationFemaleColectomy/adverse effectsbusinessAnastomotic Leak/etiology
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Physiological parameters for Prognosis in Abdominal Sepsis (PIPAS) Study: a WSES observational study

2019

Timing and adequacy of peritoneal source control are the most important pillars in the management of patients with acute peritonitis. Therefore, early prognostic evaluation of acute peritonitis is paramount to assess the severity and establish a prompt and appropriate treatment. The objectives of this study were to identify clinical and laboratory predictors for in-hospital mortality in patients with acute peritonitis and to develop a warning score system, based on easily recognizable and assessable variables, globally accepted. Background Timing and adequacy of peritoneal source control are the most important pillars in the management of patients with acute peritonitis. Therefore, early pr…

Male:Medicina Básica [Ciências Médicas]030230 surgeryLogistic regression0302 clinical medicineInjury Severity ScoreInterquartile rangeRisk FactorsAntibioticsAbdomenDiagnosisAcute peritonitis; Early warning score; Emergency surgery; Source control; Abdomen; Adult; Aged; Chi-Square Distribution; Female; Hospital Mortality; Humans; Injury Severity Score; Logistic Models; Male; Middle Aged; Risk Factors; Sepsis; PrognosisHospital MortalityMortality rateAcute peritonitilcsh:Medical emergencies. Critical care. Intensive care. First aidaarly warning scoreAcute peritonitisMiddle AgedEarly warning scorePrognosisacute peritonitis; aarly warning score; emergency surgery; source control; abdomen; adult; aged; chi-square distribution; female; hospital mortality; humans; injury severity score; logistic models; male; middle aged; risk factors; sepsis; prognosis3. Good healthManagementCiências Médicas::Medicina BásicaEmergency MedicineEmergency surgeryInjury Severity ScoreFemaleResearch ArticleHumanAdultmedicine.medical_specialtyLogistic ModelSepsilcsh:SurgeryNO03 medical and health sciencesSource controlInternal medicineSepsismedicineHumansAgedAcute appendicitisScience & TechnologyChi-Square Distributionbusiness.industryAcute peritonitis; Early warning score; Emergency surgery; Source controlRisk FactorAcute appendicitis; Antibiotics; Diagnosis; Management; SurgeryEarly warning scorelcsh:RD1-811lcsh:RC86-88.93126 Surgery anesthesiology intensive care radiologymedicine.diseaseAcute peritonitis ; Early warning score ; Emergency surgery ; Source controlLogistic ModelsObservational studySurgerybusinessChi-squared distributionKidney disease
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Pan-cancer analysis of whole genomes

2020

Publisher's version (útgefin grein)

Maletert promoter mutationsCancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2]DNA Mutational AnalysisNormal tissuesystematic analysisGermlineTranscriptome0302 clinical medicineAetiologyCàncerCellular SenescenceCancer0303 health sciencesdna-damageMassive parallel sequencingPan cancerREARRANGEMENTSHigh-Throughput Nucleotide SequencingGenomicsSciences bio-médicales et agricolesTelomereCOMPREHENSIVE3. Good healthTERT PROMOTER MUTATIONSsignatures030220 oncology & carcinogenesisScience & Technology - Other TopicsErfðarannsóknirHuman:Informàtica::Aplicacions de la informàtica::Bioinformàtica [Àrees temàtiques de la UPC]EvolutionRNA SplicingGenomicsArticleEvolution MolecularStructural variationRC025403 medical and health sciencesSDG 3 - Good Health and Well-beingGeneticgenomicsSYSTEMATIC ANALYSISGeneticsGenomics--Databases.HumansGenetic TestingMolecular BiologySIGNATURESWhole genome sequencing1000 MultidisciplinaryChromothripsisScience & TechnologyRC0254 Neoplasms. Tumors. Oncology (including Cancer)Information DisseminationResearchInstitutes_Networks_Beacons/mcrcPreventionBiology and Life SciencesMolecularOncogenesCloud Computingmedicine.diseaseGenòmicaCompute cloudsMutation570 Life sciences; biologyCOMPREHENSIVE CHARACTERIZATIONGenèticaWhole Genome Sequencing--methodsBackground informationDNA Mutational Analysis ; Evolution ; Genetic / genetics ; Genome ; Genomics ; Germ-Line Mutation / genetics ; High-Throughput Nucleotide Sequencing ; Human / genetics ; Humans ; ICGC/TCGA Pan-Cancer Analysis of Whole Genomes ConsortiumMedizinGenomeWhole-genomeGenome mappingNeoplasms2.1 Biological and endogenous factorsPromoter Regions GeneticCàncer -- Aspectes genèticsTelomeraseGeneticsWomen's cancers Radboud Institute for Molecular Life Sciences [Radboudumc 17]MultidisciplinaryChromothripsisGenomeManchester Cancer Research Centregenomics cancer profiling3rd-DAS10124 Institute of Molecular Life SciencesWomen's cancers Radboud Institute for Health Sciences [Radboudumc 17]Multidisciplinary SciencesParallel sequencingICGC/TCGA Pan-Cancer Analysis of Whole Genomes ConsortiumFemaleprofilingMedical GeneticsEngineering sciences. TechnologyBiotechnologyGeneral Science & TechnologyThe Cancer Genome Atlas610 Medicine & healthComputational biologyQH426 GeneticsBiologyConsortium of the International Cancer Genome ConsortiumPromoter RegionsGermline mutationPan-cancer analysisKrabbameinsrannsóknirmedicinecancerddc:610QH426Germ-Line MutationMedicinsk genetikKrabbamein030304 developmental biologyCell ProliferationLANDSCAPEGenome Humancomprehensive characterizationPan-cancer analysis of whole genomesPoint mutationHuman GenomeCancerReproducibility of ResultsSOMATIC MUTATIONSEVOLUTIONCancer sequencing Chromothripsis telomereDNA-DAMAGEMutagenesisPATTERNS3111 BiomedicineCHARACTERIZATION
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Search for eccentric binary black hole mergers with advanced LIGO and advanced Virgo during their first and second observing runs

2019

When formed through dynamical interactions, stellar-mass binary black holes may retain eccentric orbits ($e>0.1$ at 10 Hz) detectable by ground-based gravitational-wave detectors. Eccentricity can therefore be used to differentiate dynamically-formed binaries from isolated binary black hole mergers. Current template-based gravitational-wave searches do not use waveform models associated to eccentric orbits, rendering the search less efficient to eccentric binary systems. Here we present results of a search for binary black hole mergers that inspiral in eccentric orbits using data from the first and second observing runs (O1 and O2) of Advanced LIGO and Advanced Virgo. The search uses min…

AstrofísicaGravitació010504 meteorology & atmospheric sciencesIMPACTAstronomyWAVESBinary numberAstrophysicsgravitational waves; black hole; LIGO; VirgoLIGO-Virgo01 natural sciencesRendering (computer graphics)GravitationElliptical orbitCOMPACT-OBJECT BINARIESblack holeEccentricCOMPACT-OBJECT BINARIES; YOUNG STAR-CLUSTERS; EVOLUTION; PERTURBATIONS; PROGENITORS; IMPACT;WAVESEccentricity (behavior)LIGO010303 astronomy & astrophysicsorbitQCmedia_commonQBSettore FIS/01PhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)PROGENITORSAstrophysical black holesGravitational waves; Elliptical orbits; Astrophysical black holesPERTURBATIONSJustice and Strong Institutionsgravitational wavesPhysical SciencesAstrophysics::Earth and Planetary AstrophysicsAstrophysics - High Energy Astrophysical PhenomenaYOUNG STAR-CLUSTERSGravitational wavedata analysis methodSDG 16 - Peacemedia_common.quotation_subjectGravitational waves Elliptical orbits Astrophysical black holesFOS: Physical sciencesAstrophysics::Cosmology and Extragalactic AstrophysicsAstronomy & AstrophysicsGravitational wavesElliptical orbitsGeneral Relativity and Quantum CosmologySettore FIS/05 - Astronomia e AstrofisicaBinary black holebinary: coalescencestatistical analysis0103 physical sciencesWaveformSTFC0105 earth and related environmental sciencesScience & Technologybinary: formationVirgoSDG 16 - Peace Justice and Strong Institutionsgravitational radiationRCUKAstronomy and Astrophysics/dk/atira/pure/sustainabledevelopmentgoals/peace_justice_and_strong_institutionsLIGOEVOLUTIONgravitational radiation detectordetector: sensitivityVIRGOPhysics and Astronomyblack hole: binarySpace and Planetary Sciencegravitational radiation: emissioneccentric BBHstar: mass[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
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Search for Subsolar Mass Ultracompact Binaries in Advanced LIGO's Second Observing Run

2019

We present a search for subsolar mass ultracompact objects in data obtained during Advanced LIGO’s second observing run. In contrast to a previous search of Advanced LIGO data from the first observing run, this search includes the effects of component spin on the gravitational waveform. We identify no viable gravitational-wave candidates consistent with subsolar mass ultracompact binaries with at least one component between \ud0.2\ud \ud \udM\ud⊙\ud–\ud1.0\ud \ud \udM\ud⊙\ud. We use the null result to constrain the binary merger rate of (\ud0.2\ud \ud \udM\ud⊙\ud, \ud0.2\ud \ud \udM\ud⊙\ud) binaries to be less than \ud3.7\ud×\ud10\ud5\ud \ud \udGpc\ud−\ud3\ud \udyr\ud−\ud1\udand the binary …

Dewey Decimal Classification::500 | Naturwissenschaften::550 | Geowissenschaftenbinary: massAstrofísicaGravitacióFormation modeldensity: fluctuationAstronomyGeneral Physics and Astronomydetector: networkspin01 natural sciencesGeneral Relativity and Quantum CosmologyLIMITSblack hole: formationddc:550black holeDark MatterAstrophysics::Solar and Stellar AstrophysicsLIGOQCQBnucleus: interactionSettore FIS/01astro-ph.HEHigh Energy Astrophysical Phenomena (astro-ph.HE)gravitational wave; physics; astronomyPhysicsarticleDensity fluctuationgravitational wavesPhysical Sciences[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc]astro-ph.COAstrophysics::Earth and Planetary AstrophysicsAstrophysics - High Energy Astrophysical Phenomenablack hole: primordialGravitationAstrophysics - Cosmology and Nongalactic AstrophysicsMatter densitydensity: primordialCosmology and Nongalactic Astrophysics (astro-ph.CO)coolinggr-qcAstrophysics::High Energy Astrophysical PhenomenaPhysics MultidisciplinaryCooling mechanismPrimordial black holesFOS: Physical sciencesdark matter: densityGeneral Relativity and Quantum Cosmology (gr-qc)Astrophysics::Cosmology and Extragalactic AstrophysicsGravity wavesNuclear interactionGravitation and AstrophysicsMergingGeneral Relativity and Quantum Cosmologynull resultSettore FIS/05 - Astronomia e Astrofisicabinary: coalescence0103 physical sciencesddc:530010306 general physicsAstrophysics::Galaxy AstrophysicsSTFCScience & Technologymass: solarCosmologiaStellar evolutions010308 nuclear & particles physicsMatter fractionsgravitational radiationRCUKblack hole: massGalaxiesbinary: compactStarsgravitational radiation detectordetector: sensitivityVIRGOPhysics and Astronomygravitational radiation: emissionDewey Decimal Classification::500 | Naturwissenschaften::530 | Physik[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Gravitational waves Black holes (astronomy) Gravitational self forcePhysical Review Letters
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