0000000001212092

AUTHOR

Simon Perikles

showing 4 related works from this author

Circulating, cell-free DNA as a marker for exercise load in intermittent sports

2017

Background Attempts to establish a biomarker reflecting individual player load in intermittent sports such as football have failed so far. Increases in circulating DNA (cfDNA) have been demonstrated in various endurance sports settings. While it has been proposed that cfDNA could be a suitable marker for player load in intermittent sports, the effects on cfDNA of repeated sprinting as an essential feature in intermittent sports are unknown. For the first time, we assessed both alterations of cfDNA due to repeated maximal sprints and due to a professional football game. Methods Nine participants were subjected to a standardised sprint training session with cross-over design of five maximal s…

MalePhysiologylcsh:MedicineBiochemistryBlood Plasma796 Athletic and outdoor sports and gamesRunningMedicine and Health SciencesHumansPublic and Occupational HealthSports and Exercise Medicinelcsh:ScienceExerciseBehavior796 SportBiological Locomotionlcsh:RBiology and Life SciencesPhysical ActivitySports ScienceBody FluidsCapillariesBloodPhysical FitnessCardiovascular AnatomyRecreationBlood VesselsFemalelcsh:QAnatomyGamesCell-Free Nucleic Acidshuman activitiesBiomarkersSportsResearch Article
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P125 Internet-based exercise therapy in patients with systemic lupus erythematodes – systemic lupus erythematodes exercise program (SLEEP)

2020

Background The SLEEP study examines the effect of an exercise therapy against a control group with TAU therapy (Treatment as usual) in SLE to identify the effect of regular physical activity on muscular development. Furthermore, we investigate the effect of physical activity on disease activity and especially on fatigue syndrome. Molecular biological markers such as cfDNA and exosomes also detect the degree of the prostration of the patients. Methods Thirty SLE patients with laboratory as well as clinically stable status were included. The intervention group initially consisted of 24 patients, of which 12 were aerobically and 12 anaerobically active. In contrast, eight patients were include…

medicine.medical_specialtySystemic lupus erythematosusbusiness.industryPhysical fitnessPhysical exerciseInflammationCardiorespiratory fitnessmedicine.diseaseFibrosisInternal medicinemedicineProstrationSleep studymedicine.symptombusinessPoster presentations
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Psychodynamic Motivation and Training program (PMT) for the secondary prevention in patients with stable coronary heart disease: study protocol for a…

2013

Background Nonpharmacological secondary prevention of coronary heart disease is considered a safe and effective measure to substantially reduce mortality. Despite the effectiveness of lifestyle changes, the compliance rate of patients is very low mainly due to psychosocial barriers. Psychotherapeutic approaches that address how persons think about themselves and their behaviors appear to have a significant potential for improving health behavior. Methods/design Against this background, our study aims to examine the feasibility and effects of a Psychodynamic Motivation and Training program (PMT) as compared to one session of advice in exercise training (EX) and treatment as usual (TAU). For …

Health Knowledge Attitudes PracticeTime FactorsHealth BehaviorCoronary DiseaseStudy ProtocolCognitionSpiroergometryGermanySecondary PreventionHumansMotivationExercise ToleranceHome based exercise trainingPhysical activityRecovery of FunctionPsychodynamic psychotherapyExercise TherapyCoronary heart diseaseTreatment OutcomeResearch DesignQuality of LifeFeasibility StudiesPatient ComplianceEndothelium VascularPsychotherapy PsychodynamicRisk Reduction BehaviorBiomarkersTrials
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Use of illicit and prescription drugs for cognitive or mood enhancement among surgeons.

2012

Background Surgeons are usually exposed to high workloads leading to fatigue and stress. This not only increases the likelihood of mistakes during surgery but also puts pressure on surgeons to use drugs to counteract fatigue, distress, concentration deficits, burnout or symptoms of depression. The prevalence of surgeons taking pharmacological cognitive enhancement (CE) or mood enhancement (ME) drugs has not been systematically assessed so far. Methods Surgeons who attended five international conferences in 2011 were surveyed with an anonymous self-report questionnaire (AQ) regarding the use of prescription or illicit drugs for CE and ME and factors associated with their use. The Randomized …

AdultAged 80 and overMalePsychotropic DrugsPrescription DrugsIllicit DrugsMiddle AgedDrug UtilizationYoung AdultPhysiciansSurveys and QuestionnairesHumansSurgeon(s)FemalePrescription drug(s)Nootropic AgentsStimulant(s)AgedResearch ArticleCognitive enhancementBMC medicine
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