0000000001213251

AUTHOR

Lin Chen

showing 4 related works from this author

Numerical modeling of eastern Tibetan-type margin: Influences of surface processes, lithospheric structure and crustal rheology

2013

The eastern Tibetan margin is characterized by a steep topographic gradient and remarkably lateral variations in crustal/lithospheric structure and thermal state. GPS measurements show that the surface convergence rate in this area is strikingly low. How can such a mountain range grow without significant upper crustal shortening? In order to investigate the formation mechanism of the eastern Tibetan-type margins, we conducted 2D numerical simulations based on finite difference and marker-in-cell techniques. The numerical models were constrained with geological and geophysical observations in the eastern Tibetan margin. Several major parameters responsible for topography building, such as th…

RheologyRate of convergenceLithosphereErosionFinite differenceSedimentGeologyContext (language use)CrustGeomorphologyGeologyGondwana Research
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Search for Diphoton Events with Large Missing Transverse Energy with 36 pb^-1 of 7 TeV Proton-Proton Collision Data with the ATLAS Detector

2011

Making use of 36 pb^-1 of proton-proton collision data at sqrt{s} = 7 TeV, the ATLAS Collaboration has performed a search for diphoton events with large missing transverse energy. Observing no excess of events above the Standard Model prediction, a 95% Confidence Level (CL) upper limit is set on the cross section for new physics of sigma < 0.38 - 0.65 pb in the context of a generalised model of gauge mediated supersymmetry breaking (GGM) with a bino-like lightest neutralino, and of sigma < 0.18 - 0.23 pb in the context of a specific model with one universal extra dimension (UED). A 95 % CL lower limit of 560 GeV, for bino masses above 50 GeV, is set on the GGM gluino mass, while a low…

Physics and Astronomy (miscellaneous)Physics beyond the Standard ModelParticleProton–proton collision01 natural sciencesHigh Energy Physics - ExperimentUniversal extra dimensionHigh Energy Physics - Experiment (hep-ex)Diphoton eventsExtension[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Nuclear ExperimentPhysicsCompactification (physics)Settore FIS/01 - Fisica SperimentaleSigmaSupersymmetryATLASTransverse planePhysical SciencesDynamical Supersymmetry BreakingUniversal Extra DimensionsFísica nuclearPhenomenologyLHCPhenomenology (particle physics)Particle Physics - ExperimentParticle physicsFortran CodeSupergauge TransformationsFOS: Physical sciencesproton–proton collision; ATLAS detectorddc:500.25300103 physical sciencesFysikddc:530High Energy Physics010306 general physicsEngineering (miscellaneous)Ciencias Exactas010308 nuclear & particles physicsFísicaCollisionHadron CollidersGeneratorsCol·lisions (Física nuclear)High Energy Physics::ExperimentSupersymmetryModel
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

2021

Contains fulltext : 232759.pdf (Publisher’s version ) (Closed access) In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to…

0301 basic medicineProgrammed cell deathSettore BIO/06AutophagosomeAutolysosome[SDV]Life Sciences [q-bio]lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]Autophagy-Related ProteinsReviewComputational biology[SDV.BC]Life Sciences [q-bio]/Cellular BiologyBiologySettore MED/0403 medical and health sciencesstressChaperone-mediated autophagyddc:570AutophagyLC3AnimalsHumanscancerSettore BIO/10Autophagosome; cancer; flux; LC3; lysosome; macroautophagy; neurodegeneration; phagophore; stress; vacuoleSet (psychology)Molecular Biologyvacuole.phagophore030102 biochemistry & molecular biologyvacuolebusiness.industryInterpretation (philosophy)AutophagyAutophagosomesneurodegenerationCell BiologyfluxMulticellular organismmacroautophagy030104 developmental biologyKnowledge baselysosomeAutophagosome; LC3; cancer; flux; lysosome; macroautophagy; neurodegeneration; phagophore; stress; vacuoleBiological AssayLysosomesbusinessBiomarkers[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Autophagy

2021

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide…

macroautophagy;autophagyAutophagosome[SDV]Life Sciences [q-bio]canceLC3 macroautophagyautophagosomeneurodegeneration;[SDV.BC]Life Sciences [q-bio]/Cellular BiologyAutophagy AutophagosomeNOstress vacuolestressautophagic processesstrerfluxLC3cancerguidelinesAutophagosome; cancer; flux; LC3; lysosome; macroautophagy; neurodegeneration; phagophore; stress; vacuoleSettore BIO/06 - Anatomia Comparata E Citologia[SDV.BC] Life Sciences [q-bio]/Cellular BiologyComputingMilieux_MISCELLANEOUSMedaka oryzias latipesphagophorevacuoleQHneurodegenerationAutophagosome cancer flux LC3 lysosome macroautophagy neurodegeneration phagophore stress vacuoleautophagy; autophagic processes; guidelines; autophagosome; cancer; flux; LC3; lysosome; macroautophagy; neurodegeneration; phagophore; stress; vacuolefluxmacroautophagystress.lysosomeAutophagosome; LC3; cancer; flux; lysosome; macroautophagy; neurodegeneration; phagophore; stress; vacuoleSettore BIO/17 - ISTOLOGIARC
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