Maltoma della tiroide: presentazione di un caso clinico non associato a tiroidite di hashimoto

2005

I maltomi della tiroide sono rare neoplasie della ghiandola originati dalle cellule B parafollicolari, frequentemente associati a tiroidite autoimmune di Hashimoto. Gli Autori propongono un caso di linfoma tiroideo primitivo in cui nè l'evoluzione clinica, nè i dati strumentali e citologici preoperatori, nè l'esame istologico eseguito sul resecato chirurgico hanno evidenziato l'associazione con una tiroidite pregressa. Il caso appare interessante per la comparsa a circa 6 mesi dall'intervento di una grave forma di aplasia selettiva della serie rossa (pure red cell aplasia, PRCA) ub assenza di autoanticorpi o di segni di pregressa infezione virale, con remissione completa dopo trattamento co…

CONTRIBUTO CLINICO AL GRANULOMA EOSINOFILO DELLE OSSA IN ETA' PEDIATRICA

1979

GLI aUTORI ESAMINANO IL QUADRO CLINICO ED ANATOMO-PATOLOGICO DEL GRANULOMA EOSINOFILO DELLE OSSA E DESCRIVONO QUATTRO CASI OSSERVATI IN ETA' PEDIATRICA

Bilateral hairy polyp of the oropharynx.

1996

AbstractHairy polyp of the nasopharynx is an unusual but well-recognized entity, generally presenting as a single mass at birth or in the first year of life. We describe the clinico-pathological features of a previously unreported bilateral hairy polyp in an adult and briefly discuss the pathogenesis of this condition.

Cardiac lysosomes in doxorubicin cardiotoxicity: An ultrastructural study

1988

Value of bone marrow biopsy in the diagnosis of essential thrombocythemia.

2004

Background and Objectives. Essential thrombocythemia (ET) is a Philadelphia chromosome-negative chronic myeloproliferative disorder (CMPD) whose diagnosis, according to the Polycythemia Vera Study Group (PVSG) criteria, does not include histopathological data. The new WHO classification of CMPD has supplied new diagnostic guidelines which highlight the value of histopathology and facilitate a more precise differentiation of ET from reactive conditions and other CMPD. Design and Methods. Bone marrow biopsies from 142 adult patients diagnosed with ET according to PVSG criteria were evaluated using the new WHO classification. Megakaryocyte morphology and arrangement, amount of fibrosis and a c…

ITTERO OSTRUTTIVO COME SINTOMO DI ESORDIO IN SOGGETTO CON LEUCEMIA MONOCITICA ACUTA. CASO CLINICO

2005

Un paziente di 24 anni si è presentato alla nostra osservazione con una sintomatologia caratterizzata da dolore addominale, febbre e ittero. L'esame ecografico dell'addome mostrava una colecisti litiasica con dilatazione della via biliare principale senza immagini da riferire a calcoli nel suo interno. La colangio-RM mostrava una stenosi del terzo distale del coledoco con dilatazione del tratto a monte. Lo stesso quadro veniva mostrato da una colangiopancreatografia endoscopica retrograda. Il paziente veniva, quindi, sottoposto a laparotomia esplorativa. La colecisti non conteneva calcoli, ma nella zona infundibolare era palpabile un nodulo duro, rotondeggiante, apparentemente indovato nell…

European consensus on grading bone marrow fibrosis and assessment of cellularity.

2005

Quantification of characteristic bone marrow biopsy features includes basic parameters such as cellularity and fiber content. These are important to assess the dynamics of disease processes with a significant impact on risk stratification, survival patterns and, especially, therapy-related changes. A panel of experienced European pathologists and a foreign expert evaluated, at a multi-headed microscope, a large number of representative slides of trephine biopsies from patients with myelofibrosis in an attempt to reach a consensus on how to grade cellularity and fibrosis. This included a critical evaluation of previously described scoring systems. During the microscopic analysis and subseque…

Overexpression of interleukin-23, but not interleukin-17, as an immunologic signature of subclinical intestinal inflammation in ankylosing spondylitis

2009

Objective Subclinical gut inflammation is common in spondylarthritis, but the immunologic abnormalities underlying this process are undefined. Perturbation of the interleukin-23 (IL-23)/Th17 axis has emerged as a fundamental trigger of chronic inflammation. This study was undertaken to investigate the expression and tissue distribution of IL-23/Th17–related molecules in Crohn's disease (CD) and in subclinical gut inflammation in ankylosing spondylitis (AS). Methods Quantitative gene expression analysis of Th1/Th2 and IL-23/Th17 responses was performed in intestinal biopsy samples obtained from 12 patients with CD, 15 patients with AS, and 13 controls. IL-23 tissue distribution and identific…

Assessment of the Frequency of Additional Malignancies in Patients with Splenic Marginal Zone Lymphoma

2005

Hyperspectral techniques and GIS for archaeological investigation

2004

Aerial photos, both in colour and in black and white, have always been very important tools in archaeological surveys. Sensors, called hyperspectral, were available on the market for some years: they are able to expand the research beyond the visible area of the electromagnetic spectrum as far as the thermal infrared too. The use of these sensors, at first restricted to the applications in the traditional fields of Remote Sensing (such as, for instance, Botany, Agronomy, Geology, Hydrology), was spreading, in recent years, to some sectors, such as archaeological surveys, which were unexplored before. The presence of structures and hollows in the top subsurface is likely to cause variations …

Akt-1 a Notch-2 identificano due distinte popolazioni di carcinoma invasivo della mammella

2007