0000000001228279

AUTHOR

Barbara Więckowska

0000-0002-1811-2583

showing 1 related works from this author

Expression of selected molecular factors in two types of endometrial cancer

2021

BACKGROUND Endometrial cancers (EC) are a heterogeneous group of malignant neoplasms differing in etiology, clinical-pathological features and prognosis. OBJECTIVES To determine the differences between the expression of selected molecular factors and find connections between them in order to isolate possible biomarkers influencing treatment options. MATERIAL AND METHODS The investigated data involved archival histological preparations obtained from uterine EC samples taken from 137 patients, treated surgically between 2007 and 2014. The immunohistochemical Dako EnVisionTM Flex+ method was applied. RESULTS The expression of ERβ, MLH1 and BRCA1 was lower in ECI than in ECII patients. The ERα …

Medicine (miscellaneous)BiologyMLH1General Biochemistry Genetics and Molecular BiologyMYH9AndrologyInternal MedicinemedicineHumansPharmacology (medical)Stage (cooking)Grading (tumors)Genetics (clinical)Neoplasm StagingHeterogeneous groupFAKEndometrial cancerAdvanced stageTreatment optionsBAPPrognosismedicine.diseaseEndometrial Neoplasmsendometrial cancerReviews and References (medical)ImmunohistochemistryFemaleAdvances in Clinical and Experimental Medicine
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