0000000001229623
AUTHOR
Ariadna Lázaro
showing 11 related works from this author
Toward Near-Infrared Emission in Pt(II)-Cyclometallated Compounds: From Excimers’ Formation to Aggregation-Induced Emission
2023
Two series of Pt(II)-cyclometallated compounds containing N^C^N tridentate and alkynyl-chromophore ligands have been synthesized and structurally characterized. The N^C^N ligands differ on the presence of R1 = H or F in the central aromatic ring, while six different chromophores have been introduced to the alkynyl moiety. Single-crystal X-ray structures for some of the compounds reveal the presence of weak intermolecular contacts responsible for the formation of some dimers or aggregates. The photophysical characterization shows the presence of two emission bands in solution assigned to the 3π–π* transition from the N^C^N ligands mixed with 3MLCT/3ILCT transitions (higher energy band) in de…
Room-Temperature Phosphorescence and Efficient Singlet Oxygen Production by Cyclometalated Pt(II) Complexes with Aromatic Alkynyl Ligands
2020
The synthesis of five novel cyclometalated platinum(II) compounds containing five different alkynyl-chromophores was achieved by the reaction of the previously synthesized Pt–Cl cyclometalated compound (1) with the corresponding RC≡CH by a Sonogashira reaction. It was observed that the spectral and photophysical characteristics of the cyclometalated platinum(II) complexes (Pt–Ar) are essentially associated with the platinum-cyclometalated unit. Room-temperature emission of the Pt–Ar complexes was attributed to phosphorescence in agreement with DFT calculations. Broad nanosecond (ns)-transient absorption spectra were observed with decays approximately identical to those obtained from the emi…
Luminescent Pt-II and Pt-IV Platinacycles with Anticancer Activity Against Multiplatinum-Resistant Metastatic CRC and CRPC Cell Models
2020
Platinum-based chemotherapy persists to be the only effective therapeutic option against a wide variety of tumours. Nevertheless, the acquisition of platinum resistance is utterly common, ultimately cornering conventional platinum drugs to only palliative in many patients. Thus, encountering alternatives that are both effective and non-cross-resistant is urgent. In this work, we report the synthesis, reduction studies, and luminescent properties of a series of cyclometallated (C,N,N')PtIV compounds derived from amine- imine ligands, and their remarkable efficacy at the high nanomolar range and complete lack of cross57 resistance, as an intrinsic property of the platinacycle, against multipl…
Luminescent PtII and PtIV Platinacycles with Anticancer Activity Against Multiplatinum‐Resistant Metastatic CRC and CRPC Cell Models
2020
Abstract: Platinum‐based chemotherapy persists to be the only effective therapeutic option against a wide variety of tumours. Nevertheless, the acquisition of platinum resistance is utterly common, ultimately cornering conventional platinum drugs to only palliative in many patients. Thus, encountering alternatives that are both effective and non‐cross‐resistant is urgent. In this work, we report the synthesis, reduction studies and luminescent properties of a series of cyclometallated (C,N,N’) PtIV compounds derived from amine‐imine ligands, and their remarkable efficacy at the high nanomolar range and complete lack of cross‐resistance, as an intrinsic property of the platinacycle, against …
CCDC 1970146: Experimental Crystal Structure Determination
2020
Related Article: Ariadna Lázaro, Carla Cunha, Ramon Bosque, João Pina, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen, João Carlos Lima, Margarita Crespo, J. Sérgio Seixas de Melo, Laura Rodríguez|2020|Inorg.Chem.|59|8220|doi:10.1021/acs.inorgchem.0c00577
CCDC 1957891: Experimental Crystal Structure Determination
2020
Related Article: Ariadna Lázaro, Cristina Balcells, Josefina Quirante, Josefa Badia, Laura Baldomà, Jas S. Ward, Kari Rissanen, Mercè Font‐Bardia, Laura Rodríguez, Margarita Crespo, Marta Cascante|2020|Chem.-Eur.J.|26|1947|doi:10.1002/chem.201905325
CCDC 1958053: Experimental Crystal Structure Determination
2020
Related Article: Ariadna Lázaro, Cristina Balcells, Josefina Quirante, Josefa Badia, Laura Baldomà, Jas S. Ward, Kari Rissanen, Mercè Font‐Bardia, Laura Rodríguez, Margarita Crespo, Marta Cascante|2020|Chem.-Eur.J.|26|1947|doi:10.1002/chem.201905325
CCDC 1958051: Experimental Crystal Structure Determination
2020
Related Article: Ariadna Lázaro, Cristina Balcells, Josefina Quirante, Josefa Badia, Laura Baldomà, Jas S. Ward, Kari Rissanen, Mercè Font‐Bardia, Laura Rodríguez, Margarita Crespo, Marta Cascante|2020|Chem.-Eur.J.|26|1947|doi:10.1002/chem.201905325
CCDC 1970147: Experimental Crystal Structure Determination
2020
Related Article: Ariadna Lázaro, Carla Cunha, Ramon Bosque, João Pina, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen, João Carlos Lima, Margarita Crespo, J. Sérgio Seixas de Melo, Laura Rodríguez|2020|Inorg.Chem.|59|8220|doi:10.1021/acs.inorgchem.0c00577
CCDC 1958052: Experimental Crystal Structure Determination
2020
Related Article: Ariadna Lázaro, Cristina Balcells, Josefina Quirante, Josefa Badia, Laura Baldomà, Jas S. Ward, Kari Rissanen, Mercè Font‐Bardia, Laura Rodríguez, Margarita Crespo, Marta Cascante|2020|Chem.-Eur.J.|26|1947|doi:10.1002/chem.201905325
CCDC 1970145: Experimental Crystal Structure Determination
2020
Related Article: Ariadna Lázaro, Carla Cunha, Ramon Bosque, João Pina, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen, João Carlos Lima, Margarita Crespo, J. Sérgio Seixas de Melo, Laura Rodríguez|2020|Inorg.Chem.|59|8220|doi:10.1021/acs.inorgchem.0c00577