0000000001237362
AUTHOR
J. Rodrigo
Meta-analysis of mismatch repair polymorphisms within the cogent consortium for colorectal cancer susceptibility
In the last four years, Genome-Wide Association Studies (GWAS) have identified sixteen low-penetrance polymorphisms on fourteen different loci associated with colorectal cancer (CRC). Due to the low risks conferred by known common variants, most of the 35% broad-sense heritability estimated by twin studies remains unexplained. Recently our group performed a case-control study for eight Single Nucleotide Polymorphisms (SNPs) in 4 CRC genes. The present investigation is a followup of that study. We have genotyped six SNPs that showed a positive association and carried out a meta-analysis based on eight additional studies comprising in total more than 8000 cases and 6000 controls. The estimate…
Determination of IBIS mask transmission matrix
The high-angular resolution imager IBIS is one of the two main instruments aboard the ESA INTEGRAL satellite launched in October 2002. IBIS uses coded aperture mask technique in order to provide the required imaging capabilities for energies between 15 and 10 MeV.The precise knowledge of the coded mask response function critically determine the IBIS imaging performances. In this paper, we present a general description of the IBIS coded mask design together with its main features. Transparency and homogeneity values of the IBIS mask flight model from our laboratory measurements are presented with indication of the instrumental set-up used and accuracy achieved. Mask transmission as a functio…
XIPE: the X-ray imaging polarimetry explorer
arXiv:1309.6995v1.-- et al.