0000000001237585

AUTHOR

Roberto Bernardini

showing 5 related works from this author

Inter-society consensus for the use of inhaled corticosteroids in infants, children and adolescents with airway diseases

2021

Abstract Background In 2019, a multidisciplinary panel of experts from eight Italian scientific paediatric societies developed a consensus document for the use of inhaled corticosteroids in the management and prevention of the most common paediatric airways disorders. The aim is to provide healthcare providers with a multidisciplinary document including indications useful in the clinical practice. The consensus document was intended to be addressed to paediatricians who work in the Paediatric Divisions, the Primary Care Services and the Emergency Departments, as well as to Residents or PhD students, paediatric nurses and specialists or consultants in paediatric pulmonology, allergy, infecti…

MaleDelphi TechniqueRhinosinusitisRespiratory Tract DiseasesDelphi methodRhinosinusitiLaryngitisAdrenal Cortex HormonePediatrics0302 clinical medicineAdrenal Cortex HormonesMultidisciplinary approachInhaled corticosteroid030212 general & internal medicineChildRespiratory Tract DiseaseRhinitiSocieties MedicalRhinitiseducation.field_of_studyInhaled corticosteroidsWheezing.General MedicineSettore MED/38Systematic reviewItalyLaryngotracheitisChild PreschoolLaryngotracheitiFemalemedicine.symptomHumanmedicine.medical_specialtyConsensusAdolescentPopulationConsensuRJ1-57003 medical and health sciencesIntervention (counseling)Administration InhalationmedicineLaryngospasmHumansAdenoid hypertrophyLaryngospasmeducationIntensive care medicineAsthmaWheezingbusiness.industryResearchInfantmedicine.diseaseAsthma030228 respiratory systemAdenoid hypertrophy; Asthma; Inhaled corticosteroids; Laryngospasm; Laryngotracheitis; Rhinitis; Rhinosinusitis; Wheezingbusiness
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Management of chronic urticaria in children: a clinical guideline

2019

Abstract The aim of this guidance is to provide recommendations to clinicians and other interested parties on chronic urticaria in children. The Italian Society for Pediatrics (SIP), the Italian Society for Allergy and Immunology (SIAIP), the Italian Society for Pediatric dermatology (SIDerP) convened a multidisciplinary panel that prepared clinical guidelines for diagnosis and management of chronic urticaria in childhood. Key questions on epidemiology, natural history, diagnosis, and management were developed. The literature was systematically searched and evaluated, recommendations were rated and algorithms for diagnosis and treatment were developed. The recommendations focus on identific…

medicine.medical_specialtyUrticariaAllergyReviewPathogenesisOmalizumabOmalizumab03 medical and health sciences0302 clinical medicinePathogenesiMultidisciplinary approach030225 pediatricsEpidemiologymedicineHumans030212 general & internal medicineAngioedemaPediatric dermatologyChildChildrenChronic urticariaPediatricAngioedemabusiness.industrylcsh:RJ1-570lcsh:PediatricsGeneral MedicineGuidelineChronic urticariaChronic spontaneous urticariaSettore MED/38ManagementNatural historyInducible uricariaItalyFamily medicineTherapymedicine.symptombusinessmedicine.drugItalian Journal of Pediatrics
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Consensus statement of the Italian society of pediatric allergy and immunology for the pragmatic management of children and adolescents with allergic…

2020

AbstractThe COVID-19 pandemic has surprised the entire population. The world has had to face an unprecedented pandemic. Only, Spanish flu had similar disastrous consequences. As a result, drastic measures (lockdown) have been adopted worldwide. Healthcare service has been overwhelmed by the extraordinary influx of patients, often requiring high intensity of care. Mortality has been associated with severe comorbidities, including chronic diseases. Patients with frailty were, therefore, the victim of the SARS-COV-2 infection. Allergy and asthma are the most prevalent chronic disorders in children and adolescents, so they need careful attention and, if necessary, an adaptation of their regular…

AllergyReview030207 dermatology & venereal diseasesSettore MED/38 - Pediatria Generale E Specialistica0302 clinical medicineCOVID-19 ; Child ; Pandemic ; Allergy ; Immunologic disease ; Asthma ; AdolescentPandemicViral030212 general & internal medicineDisease management (health)ChildSocieties MedicalCOVID-19; pandemic; child; adolescent; allergy; asthma; immunologic diseaseIncidence (epidemiology)lcsh:RJ1-570Disease ManagementGeneral MedicineAtopic dermatitisSettore MED/38Adolescent; Allergy; Asthma; Child; COVID-19; Immunologic disease; Pandemic; Adolescent; COVID-19; Child; Coronavirus Infections; Decision Making; Humans; Italy; Pneumonia Viral; Pragmatic Clinical Trials as Topic; SARS-CoV-2; Allergy and Immunology; Betacoronavirus; Consensus; Disease Management; Pandemics; Societies MedicalItalyLatex allergyAdolescent; Allergy; Asthma; COVID-19; Child; Immunologic disease; PandemicCoronavirus InfectionsHumanTelemedicineConsensusAdolescentDecision MakingPneumonia ViralConsensuBetacoronavirus03 medical and health sciencesMedicalAllergy and ImmunologyPragmatic Clinical Trials as TopicmedicineHumansRisk factorPandemicsPandemicBetacoronavirubusiness.industryCoronavirus InfectionSARS-CoV-2COVID-19lcsh:PediatricsPneumoniamedicine.diseaseAsthmaAdolescent; Allergy; Asthma; Child; COVID-19; Immunologic disease; PandemicImmunologic diseaseImmunologySocietiesbusinessRare disease
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Inter-society consensus document on treatment and prevention of bronchiolitis in newborns and infants

2014

Acute bronchiolitis is the leading cause of lower respiratory t ract infection and hospitalization in children less than 1y ear of age worldwide. It is usually a mild disease, but some children may develop severe symptoms, requiring hospital admission and ventilatory support in the ICU. Infants with pre-existing risk factors (prematurity, bronchopulmonary dysplasia, congenital heart diseases and immunodeficiency) may be predisposed to a severe form of the disease. Clinical diagnosis of bronchiolitis is manly based on medical history and physical examination (rhinorrhea, cough, crackles, wheezing and signs of respiratory distress). Etiological diagnosis, with antigen or genome detection to i…

PediatricsBronchiolitis; Bronchopulmonary dysplasia; Congenital heart diseases; Immunodeficiency; Oxygen therapy; Prematurity; Prevention; Prophylaxis; Respiratory syncytial virus;ReviewRespiratory syncytial virusSeverity of Illness IndexCongenital heart diseasesSettore MED/38 - Pediatria Generale E SpecialisticaAdrenergic beta-2 Receptor AntagonistsVitamin DChildrenRespiratory distressVitaminsEnvironmental exposurePatient DischargeAnti-Bacterial AgentsBronchodilator AgentsHospitalizationSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICABronchiolitisbronchiolitisPrematuritymedicine.drugPalivizumabRespiratory Therapymedicine.medical_specialtyEpinephrineDecision MakingAntibodies Monoclonal HumanizedAntiviral AgentsIntensive Care Units NeonatalBronchiolitis Respiratory syncytial virus Prematurity Bronchopulmonary dysplasia Congenital heart diseases Immunodeficiency Oxygen therapy Prevention ProphylaxismedicineHumansImmunodeficiencyAcute bronchiolitisMedical historyConsensus DocumentIntensive care medicineGlucocorticoidsPalivizumabAsthmaSaline Solution HypertonicPrimary Health CareProphylaxisbusiness.industryNebulizers and VaporizersPreventionInfant NewbornOxygen Inhalation TherapyHumidityEnvironmental ExposureAcute bronchiolitis Consensus Documentmedicine.diseaseBronchopulmonary dysplasiaOxygen therapyHypertonic salineBronchopulmonary dysplasiaBronchiolitisbusinessItalian Journal of Pediatrics
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Cabbage and fermented vegetables: from death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19

2021

International audience; Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT1 R) axis associated with oxidative stress. This leads to insulin resistance …

ARIA groupAntioxidantMediterranean dietmedicine.medical_treatmentBrassicasulforaphaneMESH: Angiotensin-Converting Enzyme 2ReviewcabbageAntioxidants0302 clinical medicine10183 Swiss Institute of Allergy and Asthma ResearchVegetableskimchiFood sciencekimči0303 health sciencesMESH: NF-E2-Related Factor 23. Good healthAngiotensin-converting enzyme 22723 Immunology and Allergyfermentirana zelenjavaMESH: EcologyKeywords: Angiotensin converting enzyme 2NF-E2-Related Factor 2KEAP1-NRF2 SYSTEMImmunologyReviewsBrassicaNRF203 medical and health sciencesudc:578:635.34:663.15:COVID‐19angiotensin-converting enzyme 2CorrespondenceHumansMESH: SARS-CoV-2LactobacilluINTERMITTENT HYPOXIA2403 ImmunologyScience & TechnologyMESH: HumansAngiotensin II receptor type 1koronavirusMESH: Antioxidantsmedicine.disease030228 respiratory systemchemistryFermentationAllergymedicine.disease_causechemistry.chemical_compoundLINKING GUT MICROBIOTALactobacillalesLactobacillusImmunology and AllergyMESH: COVID-19Angiotensin converting enzyme 2030212 general & internal medicineOXIDATIVE STRESS[SDV.IMM.ALL]Life Sciences [q-bio]/Immunology/AllergologyKeywords: Angiotensin converting enzyme 2; COVID-19; Lactobacillus; cabbage; diet; fermented vegetable; kimchi; sulforaphane.angiotensin-converting enzyme 2; cabbage; COVID-19; diet; fermented vegetable; kimchi; Lactobacillus; sulforaphane2. Zero hungerFOODSEcologyLactobacillalesMortality rate10177 Dermatology ClinicMEDITERRANEAN DIET1107 ImmunologyLife Sciences & Biomedicinefermented vegetable610 Medicine & healthSettore MED/10 - Malattie Dell'Apparato RespiratorioBiologyMESH: FermentationMESH: Gastrointestinal MicrobiomeInsulin resistanceMESH: DietDownregulation and upregulationmedicine030304 developmental biologySARS-CoV-2COVID-19MESH: BrassicaCOVID-19; Lactobacillus; angiotensin-converting enzyme 2; cabbage; diet; fermented vegetable; kimchi; sulforaphane; Angiotensin-Converting Enzyme 2; Antioxidants; COVID-19; Diet; Ecology; Gastrointestinal Microbiome; Humans; Lactobacillales; NF-E2-Related Factor 2; Brassica; Fermentation; SARS-CoV-2; Vegetablesbiology.organism_classificationMESH: VegetablesDYSFUNCTIONDietGastrointestinal MicrobiomeLactobacillusMESH: Lactobacillalesangiotensin-converting enzyme 2 cabbage COVID-19 diet fermented vegetable kimchi Lactobacillus sulforaphanedietOxidative stressSulforaphane
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