0000000001241126

AUTHOR

S. Nair

showing 7 related works from this author

Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a…

2020

Background Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019. Methods 8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal Gaussian…

Malevery elderlyDemographic transitionHALE030204 cardiovascular system & hematologypreschool childGlobal Burden of DiseaseCarga Global de Enfermedades0302 clinical medicinenewbornRisk FactorsSurveys and Questionnairesand Risk Factors Study80 and over030212 general & internal medicineBirth RateChildMigration11 Medical and Health SciencesAged 80 and overeducation.field_of_studyInjuriesGeographyMortality rate1. No povertyDEATHCensusesGeneral MedicineSDG 10 - Reduced InequalitiesMiddle AgedDemographic analysis3142 Public health care science environmental and occupational health3. Good healthdemographic analysisEstilo de Vida SaludableGeographyrisk factorChild Preschool/dk/atira/pure/sustainabledevelopmentgoals/reduced_inequalitiesDemography/statistics & numerical dataGlobal Burden of Diseases Injuries Risk Factors Fertility Mortality Migration Population/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingepidemiologyFemaleA990 Medicine and Dentistry not elsewhere classifiedCHILD-MORTALITYLive BirthGlobal Health MetricsTRANSITIONdemographics ; GBD ; fertility ; mortality ; haleAdultAdolescentTotal fertility ratePopulationPopulation.Global Burden of Diseases Injuries and Risk Factors StudyBirth rate03 medical and health sciencesYoung AdultLife ExpectancySDG 3 - Good Health and Well-beingGeneral & Internal MedicineSYSTEMATIC ANALYSISDemografíaHumansGlobal Burden of Disease StudyhumanMortalityeducationPreschoolAgedDemographySpatial AnalysisquestionnaireInfant NewbornKlinisk medicinHIVInfantGlobal Burden of Diseasessex-specific fertilityMortality rateLive Birth/epidemiology//purl.org/pe-repo/ocde/ford#3.02.00 [https].Global Burden of DiseasesMODELFertilidadFertilityDemographic changeLife expectancyNAglobal disease burdenClinical Medicinepopulation researchDemographyThe Lancet
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Examining the generalizability of research findings from archival data

2022

This research project benefitted from Ministry of Education (Singapore) Tier 1 Grant R-313-000-131-115 (to A. Delios), National Science Foundation of China Grants 72002158 (to H.T.) and 71810107002 (to H.T.), grants from the Knut and Alice Wallenberg Foundation (to A. Dreber) and the Marianne and Marcus Wallenberg Foundation (through a Wallenberg Scholar grant; to A. Dreber), Austrian Science Fund (FWF) Grant SFB F63 (to A. Dreber), grants from the Jan Wallander and Tom Hedelius Foundation (Svenska Handelsbankens Forskningsstiftelser; to A. Dreber), and an Research & Development (R&D) research grant from Institut Européen d'Administration des Affaires (INSEAD) (to E.L.U.). Dmitrii Dubrov, o…

research reliabilityMultidisciplinaryZA4050 Electronic information resourcesDASVDP::Matematikk og Naturvitenskap: 400M-PSI/06 - PSICOLOGIA DEL LAVORO E DELLE ORGANIZZAZIONIarchival data; context sensitivity; generalizability; reproducibility; research reliabilityResearch reliability generalizability archival data reproducibility context sensitivity:Ciências Sociais::Economia e Gestão [Domínio/Área Científica]archival dataZA4050Inequality cohesion and modernizationM-PSI/03 - PSICOMETRIAVDP::Medisinske Fag: 700Ongelijkheid cohesie en moderniseringcontext sensitivitygeneralizabilityreproducibilityWork Health and Performance
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HIGH GRADE GLIOMAS AND DIPG

2014

OncologyCancer Researchmedicine.medical_specialtybusiness.industry03 medical and health sciencesAbstracts0302 clinical medicineText miningOncology030220 oncology & carcinogenesisInternal medicinemedicineNeurology (clinical)business030217 neurology & neurosurgery
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Stro-1/CD44 as putative human myometrial and fibroid stem cell markers

2015

Objective To identify and characterize myometrial/fibroid stem cells by specific stem cell markers in human myometrium, and to better understand the stem cell contribution in the development of uterine fibroids. Design Prospective, experimental human and animal study. Setting University research laboratory. Patient(s)/Animal(s) Women undergoing hysterectomy for treatment of symptomatic uterine fibroids and female NOD/SCID/IL-2Rγ null mice. Intervention(s) Identification and isolation of stem cells from human fibroids and adjacent myometrium tissues using Stro-1/CD44–specific surface markers. Main Outcome Measure(s) Flow cytometry, semiquantitative polymerase chain reaction, clonogenicity as…

AdultHomeobox protein NANOGPathologymedicine.medical_specialtyMice SCIDBiologyStem cell markerArticleMiceMice Inbred NODCancer stem cellmedicineAnimalsHumansCD90Prospective StudiesProgenitor cellMice KnockoutLeiomyomaStem CellsMesenchymal stem cellObstetrics and GynecologyHematopoietic stem cellMiddle Agedfemale genital diseases and pregnancy complicationsHyaluronan Receptorsmedicine.anatomical_structureReproductive MedicineAntigens SurfaceUterine NeoplasmsMyometriumFemaleStem cellBiomarkersFertility and Sterility
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SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
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Five insights from the Global Burden of Disease Study 2019

2020

The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD …

health care deliveryMaleHumans -- MalatiesOutcome Assessmentglobal healthDiseaseReviewinsights030204 cardiovascular system & hematologySocioeconomic FactorgeographyGlobal Burden of DiseaseNoncommunicable Diseasedisease burdenCarga Global de Enfermedades0302 clinical medicineRisk FactorsOutcome Assessment Health CareHealth careGlobal healthDelivery of health carehealth outcomesmiddle income countrybirth rate030212 general & internal medicineBirth Ratehealth outcomes health system responses economic developmentFactores de Riesgopublic healthhealth care costGeneral MedicineRisk factor (computing)humanities3. Good healthfemalepriority journalrisk factorhealth system responsesepidemiologyTERRITORIESpoliticsCLINICAL-TRIALSmedicine.medical_specialtyBirth Rate; Delivery of Health Care; Global Burden of Disease; Noncommunicable Diseases; Outcome Assessment Health Care; Risk Factors; Socioeconomic Factors; Wounds and Injuries; epidemiologyinjury2019195 COUNTRIESArticleGlobal Burden of Diseases health outcomes risk factors health system responsesHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]03 medical and health sciencessocioeconomicsmedicineSYSTEMATIC ANALYSISHumansGlobal Burden of Disease StudyhumanEpidemiologiaNoncommunicable DiseasesDisease burdenActuarial sciencehigh income countrybusiness.industryRisk FactorWounds and InjuriePublic healthagingHealth careeconomicsNon-communicable diseasemedicine.diseaseSalut públicaeconomic developmentEnfermedadesnon communicable disease//purl.org/pe-repo/ocde/ford#3.02.00 [https]Health CareRisk factorsSocioeconomic Factorspopulation growthLife expectancylife expectancyWounds and InjuriesNAPrestación de Atención de Saludglobal disease burdenbusinessDelivery of Health Carelow income country
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Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.201…

2016

non presente

Molecular Biology; Cell BiologyCell BiologySettore BIO/06 - Anatomia Comparata E CitologiaMolecular Biology
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