0000000001242941

AUTHOR

Stefanie Brassen

0000-0002-8884-7593

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Sex differences in conditioned stimulus discrimination during context-dependent fear learning and its retrieval in humans: the role of biological sex…

2015

BACKGROUND: Anxiety disorders are more prevalent in women than in men. Despite this sexual dimorphism most experimental studies are conducted in male participants and studies focusing on sex differences are sparse. In addition the role of hormonal contraceptives and menstrual cycle phase in fear conditioning and extinction processes remain largely unknown. METHODS: We investigated sex differences in context-dependent fear acquisition and extinction (day 1) and their retrieval/expression (day 2). Skin conductance responses (SCRs) fear and unconditioned stimulus expectancy ratings were obtained. RESULTS: We included 377 individuals (261 women) in our study. Robust sex differences were observe…

AdultMaleAdolescentmedia_common.quotation_subjectConditioning ClassicalPopulationExtinction PsychologicalDevelopmental psychologyYoung AdultDiscrimination PsychologicalContraceptive Agents FemalemedicineHumansPharmacology (medical)Fear conditioningDiscrimination learningeducationMenstrual CycleBiological PsychiatryMenstrual cyclemedia_commonSex Characteristicseducation.field_of_studyAssociation LearningFearGalvanic Skin ResponseExtinction (psychology)Anticipation PsychologicalMenstrual cycle phasePsychiatry and Mental healthAnxietyFemalemedicine.symptomPsychologyResearch PaperClinical psychologySex characteristicsJournal of Psychiatry and Neuroscience
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