0000000001247579

AUTHOR

Elina Ortisi

showing 8 related works from this author

Surgical management of retinal detachment because of macular hole in highly myopic eyes

2012

PURPOSE: The purpose of this study was to review the current management of macular hole retinal detachment in highly myopic eyes. METHODS: We searched English MEDLINE databases from January 1997 to January 2011 for surgical management of macular hole retinal detachment in highly myopic eyes. The main outcomes reported include retinal reattachment and visual acuity after primary surgery. RESULTS: Surgical procedures including pneumoretinopexy, pars plana vitrectomy with gas or silicone oil tamponade with or without laser therapy around the macular hole, and macular buckling have been the primary treatment choices. New techniques, including internal limiting membrane or epiretinal membrane pe…

medicine.medical_specialtygenetic structureshighly myopic eyeEndotamponadeOphthalmologic Surgical ProceduresRetinal detachment surgeryOphthalmologymedicineHumansMacular holetreatmentbusiness.industryRetinal DetachmentRetinal detachmentGeneral Medicinemedicine.diseaseRetinal Perforationseye diseasesmacular holeOphthalmologyCurrent managementMyopia DegenerativeRetinal Perforationsense organsbusinessOphthalmologic Surgical ProcedureHuman
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Preoperative, Intraoperative and Postoperative Corticosteroid Use as an Adjunctive Treatment for Rhegmatogenous Retinal Detachment

2020

The treatment for rhegmatogenous retinal detachment (RRD) is surgery, including pars plana vitrectomy (PPV) and scleral buckling (SB). Despite surgical advances, degeneration of the photoreceptors and post-operative complications, such as proliferative vitreoretinopathy (PVR), often occurs as the result of inflammation, preventing complete visual recovery or causing RRD recurrence. There is increasing evidence that in the presence of RRD, the activation of inflammatory processes occurs and the surgery itself induces an inflammatory response. This comprehensive review focuses on the use of different formulations of corticosteroids (CCS), as an adjunctive treatment to surgery, either PPV or S…

Pars planamedicine.medical_specialtyProliferative vitreoretinopathyTriamcinolone acetonidemedicine.medical_treatmentvitrectomylcsh:MedicineVitrectomydexamethasoneReviewtriamcinolonecorticosteroids03 medical and health sciences0302 clinical medicinefluocinolonecorticosteroids; dexamethasone; fluocinolone; rhegmatogenous retinal detachment; scleral buckling; triamcinolone; vitrectomyPrednisoneMedicineCorticosteroidscleral bucklingSettore MED/30 - Malattie Apparato Visivobusiness.industrylcsh:Rrhegmatogenous retinal detachmentRetinal detachmentGeneral MedicineFluocinolonemedicine.diseaseeye diseasesSurgerymedicine.anatomical_structureAdjunctive treatment030221 ophthalmology & optometrybusiness030217 neurology & neurosurgerymedicine.drug
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Vascular changes after vitrectomy for rhegmatogenous retinal detachment: optical coherence tomography angiography study

2020

Purpose: To analyse the postoperative foveal avascular zone (FAZ) area, superficial vessel density (SVD) and deep vessel density (DVD) and their correlation with functional (best-corrected visual acuity, BCVA) and anatomical outcomes (foveal macular thickness, FMT) after surgery for rhegmatogenous retinal detachment (RRD) repair. Method: Patients with RRD eyes, successfully treated with a single pars plana vitrectomy (PPV) with gas tamponade and a minimum 12 months follow-up, were re-examined. Foveal avascular zone (FAZ) area, SVD, DVD and FMT were evaluated by using optical coherence tomography angiography (OCTA) and compared to fellow eye. Results: Fifty-six patients with macula-on and 37…

Pars planamedicine.medical_specialtyVisual acuitygenetic structuresmedicine.medical_treatmentvitrectomyVitrectomyfoveal avascular zone03 medical and health scienceschemistry.chemical_compound0302 clinical medicineFovealOphthalmologyMedicinebusiness.industryrhegmatogenous retinal detachmentRetinal detachmentRetinalGeneral MedicineOptical coherence tomography angiographymedicine.diseaseeye diseasesOphthalmologymedicine.anatomical_structuresuperficial and deep vessel densitychemistry030221 ophthalmology & optometryfoveal avascular zone; rhegmatogenous retinal detachment; superficial and deep vessel density; vitrectomysense organsTamponademedicine.symptombusiness030217 neurology & neurosurgery
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Modified Vitrectomy Technique for Phakic Rhegmatogenous Retinal Detachment with Intermediate Break

2018

Purpose. To evaluate the effects of a modification of the traditional 25-gauge pars plana vitrectomy technique in the treatment of uncomplicated macula-on rhegmatogenous retinal detachment (RRD) with intermediate retinal break(s) and marked vitreous traction in the phakic eye. Methods. Prospective, noncomparative, and interventional case series. All consecutive phakic eyes with primary uncomplicated macula-on RRD with intermediate retinal break(s) and marked vitreous traction, with at least 1 year of postoperative follow-up, were enrolled. In all eyes, “localized 25-gauge vitrectomy” under air infusion with localized removal of the vitreous surrounding the retinal break(s), in association w…

0301 basic medicinePars planamedicine.medical_specialtygenetic structuresArticle Subjectmedicine.medical_treatmentScheimpflug principlevitrectomyVitrectomy03 medical and health scienceschemistry.chemical_compound0302 clinical medicinelcsh:OphthalmologyOphthalmologymedicineMacular edemabusiness.industryRetinal detachmentRetinalmedicine.diseaseeye diseasesOphthalmology030104 developmental biologymedicine.anatomical_structurechemistrylcsh:RE1-994030221 ophthalmology & optometryClinical StudyTamponadesense organsEpiretinal membranebusiness
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Intravitreal Dexamethasone Implant for Postoperative Macular Oedema Secondary to Vitrectomy for Epiretinal Membrane and Retinal Detachment: A Systema…

2021

Purpose. To evaluate the efficacy of intravitreal dexamethasone implant (DEX) for the treatment of macular oedema secondary to vitrectomy for epiretinal membrane (ERM) and retinal detachment (RD) by conducting a systematic review with meta-analysis of published studies. Methods. Studies reporting clinical outcomes of DEX use for the treatment of macular oedema secondary to ERM and RD vitrectomy were searched on PubMed and Embase databases. The primary outcome was best-corrected visual acuity (BCVA) change between baseline and post-DEX treatment, reported as mean difference (MD) with 95% confidence interval (CI). Mean central macular thickness (CMT) change was assessed as a secondary outcome…

medicine.medical_specialtyVisual acuitygenetic structuresmedicine.medical_treatmentPopulationVitrectomyReview Articlelaw.inventionRandomized controlled triallawOphthalmologymedicineeducationDexamethasoneeducation.field_of_studybusiness.industryRetinal detachmentRE1-994medicine.diseaseConfidence intervalmacular oedema intravitreal dexamethasone implant (DEX) vitrectomy epiretinal membrane (ERM) retinal detachment (RD).OphthalmologyEpiretinal membranemedicine.symptombusinessmedicine.drug
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Optical coherence tomography angiography evaluation of peripapillary microvascular changes after rhegmatogenous retinal detachment repair

2021

PURPOSE To evaluate the radial peripapillary capillary plexus (RPCP) vessel density (VD) and the retinal nerve fiber layer (RNFL) thickness in eyes successfully treated with pars plana vitrectomy for primary rhegmatogenous retinal detachment. METHODS In this cross-sectional multicenter clinical study, eyes with a minimum 12-month follow-up were reexamined. The RPCP VD and RNFL thickness in the rhegmatogenous retinal detachment subfields of the affected eye (study group) were compared with the corresponding areas of the healthy fellow eyes (control group). RESULTS Fifty-three eyes were included in the study. A significantly lower RPCP VD and RNFL thickness were observed in those subfields af…

MaleRetinal Ganglion Cellsgenetic structuresComputed Tomography Angiographymedicine.medical_treatmentNerve fiber layerVisual AcuityVitrectomyEyeradial peripapillary capillary plexuschemistry.chemical_compoundNerve FibersVitrectomyTomographyRetinal detachment repairRetinal detachmentGeneral MedicineMiddle AgedAxial Length Eyemedicine.anatomical_structureFemaleTomography Optical CoherencePars planamedicine.medical_specialtyBiometryOptic DiskEndotamponaderetinal detachmentOCT-angiography; Radial peripapillary capillary plexus; Retinal detachment; Retinal nerve fiber layer; Aged; Axial Length Eye; Biometry; Cross-Sectional Studies; Endotamponade; Female; Humans; Male; Middle Aged; Nerve Fibers; Optic Disk; Retinal Detachment; Retinal Ganglion Cells; Retinal Vessels; Retrospective Studies; Visual Acuity; Computed Tomography Angiography; Tomography Optical Coherence; VitrectomyOphthalmologymedicineHumansAxial LengthAgedRetrospective StudiesRetinabusiness.industryradial peripapillary capillary plexus; OCT-angiography; retinal nerve fiber layer; retinal detachmentRetinal Vesselsretinal nerve fiber layerRetinalOptical coherence tomography angiographymedicine.diseaseeye diseasesOphthalmologyCross-Sectional StudieschemistryOptical Coherencesense organsOCT-angiographybusiness
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TGF-β Serum Levels in Diabetic Retinopathy Patients and the Role of Anti-VEGF Therapy.

2020

Transforming growth factor &beta

0301 basic medicinePlacental growth factorMaleVascular Endothelial Growth Factor Aserum biomarkersGastroenterologylcsh:ChemistryPathogenesischemistry.chemical_compound0302 clinical medicineTransforming Growth Factor betaMedicineMolecular Targeted Therapylcsh:QH301-705.5SpectroscopyAfliberceptAged 80 and overGeneral MedicineDiabetic retinopathyTGFComputer Science ApplicationsVascular endothelial growth factor ABiomarker (medicine)Intercellular Signaling Peptides and ProteinsFemaleTomography Optical Coherencemedicine.drugmedicine.medical_specialtyanti-VEGFAAnti-VEGFA; Diabetic retinopathy; Serum biomarkers; TGFCatalysisArticleProinflammatory cytokineInorganic Chemistry03 medical and health sciencesTGFβInternal medicineHumansPhysical and Theoretical ChemistryMolecular BiologyAgedDiabetic Retinopathybusiness.industryOrganic Chemistrymedicine.diseaseeye diseases030104 developmental biologylcsh:Biology (General)lcsh:QD1-999chemistryDiabetes Mellitus Type 2ROC Curve030221 ophthalmology & optometryGlycated hemoglobinbusinessBiomarkersInternational journal of molecular sciences
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OCT-Angiography evaluation of peripapillary microvascular changes after rhegmatogenous retinal detachment repair

2021

Purpose: To evaluate the radial peripapillary capillary plexus (RPCP) vessel density (VD) and the retinal nerve fiber layer (RNFL) thickness in eyes successfully treated with pars plana vitrectomy for primary rhegmatogenous retinal detachment. Methods: In this cross-sectional multicenter clinical study, eyes with a minimum 12-month follow-up were reexamined. The RPCP VD and RNFL thickness in the rhegmatogenous retinal detachment subfields of the affected eye (study group) were compared with the corresponding areas of the healthy fellow eyes (control group). Results: Fifty-three eyes were included in the study. A significantly lower RPCP VD and RNFL thickness were observed in those subfields…

Retinal nerve fiber layerRadial peripapillary capillary plexusOCT-Angiography
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