0000000001263540

AUTHOR

S Carbone

showing 3 related works from this author

MODELLI DI STUDIO DI BIOMARKERS PER LA VALUTAZIONE DEL RISCHIO DI CONTAMINAZIONE DA NANOPARTICELLE D’ARGENTO NEL SUOLO (PROGETTO INESE)

2013

Il progetto “Impact of Nanoparticles in Environmental Sustainability and Ecotoxicity” (INESE), finanziato dall’Istituto Italiano di Tecnologia (IIT), ha studiato gli effetti delle nanoparticelle (NPs) ingegnerizzate su diversi ecosistemi (acquatici e terrestri), proponendo differenti sistemi biologici di studio (piante acquatiche, ricci di mare, organismi del suolo, pomodoro-impollinatore, ecc). In particolare l’UO dell’Università di Bologna ha focalizzato l’attenzione sullo studio dei modelli di interazione tra particelle di suolo, microorganismi (biomassa microbica), invertebrati (Lumbricus rubellus) e pianta (Solanum lycopersicum). In questa sede verranno riportati i risultati ottenuti d…

Nanoparticelle di argentolombrichiSettore AGR/13 - Chimica Agrariacolture agrariebiodisponibilitàbiomassa microbicaESEM-EDS.
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Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately …

2017

Background The best treatment option for patients with type 2 diabetes in whom treatment with metformin alone fails to achieve adequate glycaemic control is debated. We aimed to compare the long-term effects of pioglitazone versus sulfonylureas, given in addition to metformin, on cardiovascular events in patients with type 2 diabetes. Methods TOSCA.IT was a multicentre, randomised, pragmatic clinical trial, in which patients aged 50–75 years with type 2 diabetes inadequately controlled with metformin monotherapy (2–3 g per day) were recruited from 57 diabetes clinics in Italy. Patients were randomly assigned (1:1), by permuted blocks randomisation (block size 10), stratified by site and…

MaleDiabetes and Metabolism ipoglycemic drugs cardiovascualr eventSettore MED/09 - Medicina Internaendocrine system diseasesIMPACTpioglitazone versus sulfonylureasEndocrinology Diabetes and MetabolismGLIMEPIRIDEDiabetes cardiovascular events metformin pioglitazone sulphonylureasType 2 diabetes030204 cardiovascular system & hematologyInternal Medicine; Endocrinology Diabetes and Metabolism; Endocrinologylaw.inventionSettore MED/13 - EndocrinologiaGlibenclamide0302 clinical medicineRandomized controlled triallawGLYCEMIC CONTROLGliclazideInternal medicinediabetes and metabolismRISKeducation.field_of_studydiabetesIncidenceInternal medicine; endocrinology diabetes and metabolism; endocrinologyMiddle AgedINSULINMetforminMetforminTreatment OutcomeEditorialsulphonylureasCardiovascular DiseasesCombinationDrug Therapy CombinationFemaleType 2medicine.drugmedicine.medical_specialtyPopulation030209 endocrinology & metabolismAged; Cardiovascular Diseases; Diabetes Mellitus Type 2; Drug Therapy Combination; Female; Humans; Hypoglycemic Agents; Incidence; Male; Metformin; Middle Aged; Pioglitazone; Sulfonylurea Compounds; Thiazolidinediones; Treatment OutcomeCardiovascular events03 medical and health sciencesendocrinologyGLUCOSE-LOWERING DRUGSDrug TherapyInternal medicineDiabetes MellitusmedicineHumansHypoglycemic AgentssulfonylureaseducationTOSCA.ITAgedPioglitazonebusiness.industryMORTALITYnutritional and metabolic diseasesInsulin resistancemedicine.diseaseSurgeryGlimepirideSulfonylurea CompoundsDiabetes Mellitus Type 2Diabetes Mellitus; Pioglitazone; Insulin resistanceThiazolidinedionesbusinessFOLLOW-UPPioglitazone
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Impact of Ag and Co engineered nanoparticles on soil microbial community structure in a soil perturbed by Lumbricus rubellus

2014

Knowledge on the impact of engineered nanomaterials (ENMs) on both human and environment health is scarce. Several studies sustain that soil is the environmental compartment designed to be the major recipient of engineered nanoparticles (NPs). With the aim of investigating the impact of commercially relevant NPs on soil functioning, we compared the effect of Ag and Co NPs, as well as cobalt and silver ions, on soil microbial community in the presence of Lumbricus rubellus. Earthworms specimens were placed in a rich‐C soil and fed with horse manure spiked with Ag‐NPs, Co‐NPs, Ag+ and Co2+ for a total amount of 10 mg of single pollutant kg‐1 soil. At the end of acute exposure (4 weeks) to pol…

Co NanoparticleSoil microbial biomaSettore AGR/13 - Chimica AgrariaAg NanoparticleLumbricus rubelluPLFAs
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