0000000001265083

AUTHOR

Ryder S. D.

showing 1 related works from this author

Treatment with tenofovir disoproxil fumarate or entecavir in chronic hepatitis B virus-infected patients with renal impairment: results from a 7-year…

2020

BackgroundLimited data exist regarding tenofovir disoproxil fumarate (TDF) safety and effectiveness in chronic hepatitis B virus-infected (CHB) patients with renal impairment (RI).AimsTo compare real-world data on renal safety and effectiveness of TDF vs entecavir (ETV) in CHB patients with moderate-to-severe RI.MethodsRetrospective, non-interventional, cohort study analysing medical records for TDF/ETV-treated CHB patients (54 European centres). Included patients experienced moderate-to-severe RI (creatinine clearance 20-60 mL/min [Cockcroft-Gault]) either before TDF/ETV initiation ('before' subgroup [baseline = treatment initiation]) or after TDF/ETV initiation ('after' subgroup [baseline…

MaleAdultmedicine.medical_specialtyGuanineTenofovirMEDLINEAntiviral AgentsVirus03 medical and health sciencesYoung Adult0302 clinical medicineHepatitis B ChronicRetrospective StudieInternal medicine80 and overHBVMedicineHumansPharmacology (medical)030212 general & internal medicineRenal InsufficiencyYoung adultAdult; Aged; Aged 80 and over; Antiviral Agents; Female; Guanine; Hepatitis B Chronic; Humans; Male; Middle Aged; Renal Insufficiency; Retrospective Studies; Tenofovir; Treatment Outcome; Young AdultChronicTenofovirAgedRetrospective StudiesAged 80 and overAntiviral AgentHepatologybusiness.industryGastroenterologyvirus diseasesRetrospective cohort studyEntecavirHepatitis BMiddle Agedmedicine.diseaseHepatitis BTreatment OutcomeCohort030211 gastroenterology & hepatologyFemalebusinessmedicine.drugHuman
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