0000000001269967

AUTHOR

G Ruggiero

showing 5 related works from this author

Randomised study comparing 48 and 96 weeks peginterferon α-2a therapy in genotype D HBeAg-negative chronic hepatitis B

2013

Treatment with peginterferon α-2a (PegIFN) for 48 weeks is the standard of care for selected HBeAg-negative patients chronically infected with hepatitis B virus (HBV), but with limited treatment efficacy. A study was undertaken to investigate whether treatment extension to 96 weeks improves the outcome in this patient population.128 HBeAg-negative patients (120 genotype D) were randomised to weekly 180 μg PegIFN for 48 weeks (group A, n=51), 180 μg PegIFN for 48 weeks followed by 135 μg weekly for an additional 48 weeks (group B, n=52) or 180 μg PegIFN plus lamivudine (100 mg/day) for 48 weeks then 135 μg PegIFN for 48 weeks (group C, n=25). Endpoints were alanine aminotransferase normalisa…

AdultMaleHBsAgmedicine.medical_specialtyHepatitis B virusTime FactorsAnti-HIV Agentsmedicine.disease_causeGastroenterologyAntiviral AgentsGroup Blaw.inventionPolyethylene GlycolsPharmacotherapyHepatitis B ChronicRandomized controlled triallawPegylated interferonInternal medicinemedicineHumansHepatitis B e AntigensHepatitis B virusbusiness.industryGastroenterologyLamivudineInterferon-alphaAlanine TransaminaseHepatitis BMiddle Agedmedicine.diseaseHepatitis BRecombinant ProteinsTreatment OutcomeLamivudineImmunologyDNA ViralInterferonDrug Therapy CombinationFemaleHepatitis B; Interferonbusinessmedicine.drug
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Search for K+ decays to a muon and invisible particles

2021

The NA62 experiment at CERN reports searches for $K^+\to\mu^+N$ and $K^+\to\mu^+\nu X$ decays, where $N$ and $X$ are massive invisible particles, using the 2016-2018 data set. The $N$ particle is assumed to be a heavy neutral lepton, and the results are expressed as upper limits of ${\cal O}(10^{-8})$ of the neutrino mixing parameter $|U_{\mu4}|^2$ for $N$ masses in the range 200-384 MeV/$c^2$ and lifetime exceeding 50 ns. The $X$ particle is considered a scalar or vector hidden sector mediator decaying to an invisible final state, and upper limits of the decay branching fraction for $X$ masses in the range 10-370 MeV/$c^2$ are reported for the first time, ranging from ${\cal O}(10^{-5})$ t…

Nuclear and High Energy PhysicsScalar (mathematics)FOS: Physical sciences01 natural sciences7. Clean energyNA62High Energy Physics - ExperimentNuclear physicsHigh Energy Physics - Experiment (hep-ex)0103 physical sciencesheavy neutral leptonsDark sector NA62physics beyond Standard Model010306 general physicsPhysicsRange (particle radiation)Muonkaon decays010308 nuclear & particles physicsBranching fractionDark sectorSettore FIS/04Kaonslcsh:QC1-999Hidden sectorParticleHigh Energy Physics::ExperimentNeutrinoParticle Physics - Experimentlcsh:PhysicsLepton
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The beam and detector of the NA62 experiment at CERN

2017

NA62 is a fixed-target experiment at the CERN SPS dedicated to measurements of rare kaon decays. Such measurements, like the branching fraction of the $K^{+} \rightarrow \pi^{+} \nu \bar\nu$ decay, have the potential to bring significant insights into new physics processes when comparison is made with precise theoretical predictions. For this purpose, innovative techniques have been developed, in particular, in the domain of low-mass tracking devices. Detector construction spanned several years from 2009 to 2014. The collaboration started detector commissioning in 2014 and will collect data until the end of 2018. The beam line and detector components are described together with their early …

Particle physicsPhysics - Instrumentation and DetectorsPhysics::Instrumentation and DetectorsFOS: Physical scienceslarge detector systems for particle and astroparticle physicsCalorimeters; Cherenkov detectors; Large detector systems for particle and astroparticle physics; Particle tracking detectors; Instrumentation; Mathematical PhysicsNA62 experimentTracking (particle physics)7. Clean energy01 natural sciencesParticle detectorHigh Energy Physics - ExperimentSettore FIS/04 - Fisica Nucleare e SubnucleareNONuclear physicsmathematical physicsHigh Energy Physics - Experiment (hep-ex)Calorimeters0103 physical sciencesparticle tracking detectorsDetectors and Experimental Techniques010306 general physicsParticle Physicsphysics.ins-detCalorimeters; Cherenkov detectors; large detector systems for particle and astroparticle physics; particle tracking detectors; instrumentation; mathematical physicsPhysicsinstrumentationCalorimeterLarge Hadron Collider010308 nuclear & particles physicsBranching fractionhep-exDetectorCherenkov detectorsInstrumentation and Detectors (physics.ins-det)Particle tracking detectorBeamlineLarge detector systems for particle and astroparticle physicHigh Energy Physics::ExperimentBeam (structure)Particle Physics - ExperimentCherenkov detector
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The beam and detector for the NA48 neutral kaon CP violation experiment at CERN

2007

The beam and detector, used for the NA48 experiment, devoted to the measurement of Re (ε{lunate}′ / ε{lunate}), and for the NA48/1 experiment on rare KS and neutral hyperon decays, are described. © 2007 Elsevier B.V. All rights reserved.

Nuclear and High Energy PhysicsParticle physicsacceleratoriNA62 experiment01 natural sciencesLIQUID-KRYPTON CALORIMETERDECAYSNOfasci di particelleKaon beamsNuclear physicsDRIFT CHAMBER ELECTRONICSCERNViolazione di CP0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Kaon decaysdetector; CP violation; Kaon decays010306 general physicsInstrumentation07.05.Fb; 13.20.Eb; 29.40.Vj; 29.27.EgPhysicsCalorimeterLarge Hadron ColliderdetectorCRYSTAL010308 nuclear & particles physicsLIQUID-KRYPTON CALORIMETER; DRIFT CHAMBER ELECTRONICS; PROTON TAGGING DETECTOR; PC FARM; TRIGGER; SYSTEM; READOUT; DECAYS; PERFORMANCE; CRYSTALDetectorPC FARMHyperonNA48 experimentDetectorsMagnetic spectrometerPERFORMANCErivelatoriREADOUTkaon decayCalorimeterTriggerCP violationfasci di particelle; acceleratori; CERN; Violazione di CP; rivelatori; kaon decayCP violationHigh Energy Physics::ExperimentParticle Physics - ExperimentPROTON TAGGING DETECTORSYSTEMBeam (structure)
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Kaon physics at the CERN-SPS

2015

The NA48/2 and NA62 collaborations report on recent results, current status, and prospects of kaon physics at the CERN-SPS. The NA62 collaborations aims to measure the decay [Formula: see text] with an uncertainty of 10% or better. The NA62 detector and preliminary results from a pilot run in 2014 are presented. In addition, recent results of the NA48/2 collaboration are reported. A search for Dark Photons has been performed in [Formula: see text] decays via the kaon decays [Formula: see text] and [Formula: see text]. No dark photon signal was observed and new upper limits on the mixing parameter [Formula: see text] and the dark photon mass were computed. We also report the first observati…

Nuclear physicsPhysicsParticle physicsLarge Hadron ColliderPhotonDetectorMeasure (physics)High Energy Physics::ExperimentMixing (physics)Dark photonSettore FIS/04 - Fisica Nucleare e Subnucleare
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